Irene L Andrulis
Overview
Explore the profile of Irene L Andrulis including associated specialties, affiliations and a list of published articles.
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393
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19211
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Recent Articles
1.
Yiangou K, Mavaddat N, Dennis J, Zanti M, Wang Q, Bolla M, et al.
Breast Cancer Res
. 2024 Dec;
26(1):189.
PMID: 39734228
Background: The 313-variant polygenic risk score (PRS) provides a promising tool for clinical breast cancer risk prediction. However, evaluation of the PRS across different European populations which could influence risk...
2.
MacInnis R, Jenkins M, Milne R, John E, Daly M, Andrulis I, et al.
JNCI Cancer Spectr
. 2024 Dec;
9(1).
PMID: 39673461
Menopausal users of hormone replacement therapy (HRT) are at increased breast cancer risk and decreased colorectal cancer (CRC) risk compared with individuals who have never used HRT, but these opposing...
3.
Farncombe K, Hughes L, Tuzlali E, Akbari M, Andrulis I, Aronson M, et al.
BMJ Open
. 2024 Nov;
14(11):e087023.
PMID: 39581712
Introduction: In Canada, care for individuals with hereditary cancer is fragmented across the provinces and territories, with carriers of pathogenic variants in cancer-susceptibility genes seeing multiple doctors and often advocating...
4.
Principe M, Gokgoz N, Prochazka P, Coward V, Saini S, MacParland S, et al.
Ann Surg Oncol
. 2024 Nov;
32(3):1511-1521.
PMID: 39556178
Background: Peritumoral edema on staging magnetic resonance imaging (MRI) is associated with higher local recurrence in soft tissue sarcoma (STS). This may relate to the presence of satellite malignant cells...
5.
Darville-OQuinn P, Gokgoz N, Tsoi K, Andrulis I, Wunder J
J Clin Med
. 2024 Nov;
13(21).
PMID: 39518682
: Sarcomas are a heterogeneous group of cancers, many with high rates of recurrence and metastasis, leading to significant morbidity and mortality. Due to a lack of early diagnostic biomarkers,...
6.
Kehm R, Genkinger J, Knight J, Maclnnis R, MacInnis R, Liao Y, et al.
Cancer Epidemiol Biomarkers Prev
. 2024 Oct;
34(1):108-116.
PMID: 39404779
Background: Breast cancer incidence is increasing in women under age 40, underscoring the need for research on breast cancer risk factors for younger women. Methods: We used data from an...
7.
Beird H, Cloutier J, Gokgoz N, Eeles C, Griffin A, Ingram D, et al.
Lab Invest
. 2024 Oct;
104(11):102146.
PMID: 39357799
A solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm that can arise at any anatomical site and is characterized by recurrent NAB2::STAT6 fusions and metastatic progression in 10% to...
8.
Phillips K, Kotsopoulos J, Domchek S, Terry M, Chamberlain J, Bassett J, et al.
J Clin Oncol
. 2024 Oct;
43(4):422-431.
PMID: 39356978
Purpose: It is uncertain whether, and to what extent, hormonal contraceptives increase breast cancer (BC) risk for germline or mutation carriers. Methods: Using pooled observational data from four prospective cohort...
9.
Zanti M, OMahony D, Parsons M, Dorling L, Dennis J, Boddicker N, et al.
medRxiv
. 2024 Sep;
PMID: 39281752
Clinical genetic testing identifies variants causal for hereditary cancer, information that is used for risk assessment and clinical management. Unfortunately, some variants identified are of uncertain clinical significance (VUS), complicating...
10.
McDonald J, Liao Y, Knight J, John E, Kurian A, Daly M, et al.
JAMA Netw Open
. 2024 Aug;
7(8):e2427441.
PMID: 39186276
Importance: Few studies have investigated whether the associations between pregnancy-related factors and breast cancer (BC) risk differ by underlying BC susceptibility. Evidence regarding variation in BC risk is critical to...