Tarek M El-Achkar
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Explore the profile of Tarek M El-Achkar including associated specialties, affiliations and a list of published articles.
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88
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1896
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Recent Articles
1.
Williams Jr J, El-Achkar T
Urolithiasis
. 2025 Feb;
53(1):34.
PMID: 39960517
Kidney stone disease has long been thought to involve tissue inflammation, but direct evidence linking inflammation as a causative factor in human stone formation remains limited. This review focuses on...
2.
Bond C, Bednarski O, Datta D, Namazzi R, Opoka R, Lima-Cooper G, et al.
Nat Med
. 2025 Jan;
PMID: 39856335
We investigated the role of uric acid in the pathogenesis of severe malaria (SM) in two independent cohorts of children with SM. Hyperuricemia (blood uric acid ≥ 7 mg dl)...
3.
Ferreira R, Gisch D, Phillips C, Cheng Y, Asthana M, Lake B, et al.
bioRxiv
. 2025 Jan;
PMID: 39803522
The maintenance of a healthy epithelial-endothelial juxtaposition requires cross-talk within glomerular cellular niches. We sought to understand the spatially-anchored regulation and transition of endothelial and mesangial cells from health to...
4.
Asghari M, Sabo A, Barwinska D, Ferreira R, Ferkowicz M, Bowen W, et al.
bioRxiv
. 2024 Dec;
PMID: 39677736
The organizational principles of nephronal segments are based on longstanding anatomical and physiological attributes that are closely linked to the homeostatic functions of the kidney. Novel molecular approaches have recently...
5.
Golestaneh L, Basalely A, Linkermann A, El-Achkar T, Kim R, Neugarten J
Am J Kidney Dis
. 2024 Oct;
85(3):329-338.e1.
PMID: 39447957
Rationale & Objective: Animal models of kidney disease suggest a protective role for female sex hormones, but some authorities assert that female sex in humans is a risk factor for...
6.
Williams Jr J, Bowen W, Lingeman J, Rivera M, Worcester E, El-Achkar T
Urolithiasis
. 2024 Sep;
52(1):133.
PMID: 39340639
Endoscopic and biopsy findings have identified two distinct phenotypes among individuals with calcium oxalate (CaOx) kidney stones. The first type has normal renal papillae but shows interstitial mineral deposition, known...
7.
Ghajar-Rahimi G, Barwinska D, Whipple G, Kamocka M, Khan S, Winfree S, et al.
Am J Physiol Renal Physiol
. 2024 Sep;
327(5):F869-F884.
PMID: 39323387
The long-term effects of a single episode of acute kidney injury (AKI) induced by bilateral ischemia-reperfusion injury (BIRI) on kidney lymphatic dynamics are not known. The purpose of this study...
8.
Williams Jr J, Bowen W, Lingeman J, Rivera M, Worcester E, El-Achkar T
Res Sq
. 2024 Sep;
PMID: 39281877
Endoscopic and biopsy findings have identified two distinct phenotypes among individuals with calcium oxalate (CaOx) kidney stones. One phenotype exhibits normal renal papillae but shows interstitial mineral deposition, known as...
9.
Schmidt I, Surapaneni A, Zhao R, Upadhyay D, Yeo W, Schlosser P, et al.
Nat Commun
. 2024 Aug;
15(1):7368.
PMID: 39191768
The kidney tubules constitute two-thirds of the cells of the kidney and account for the majority of the organ's metabolic energy expenditure. Acute tubular injury (ATI) is observed across various...
10.
Nanamatsu A, de Araujo L, LaFavers K, El-Achkar T
Nat Rev Nephrol
. 2024 Aug;
20(12):806-821.
PMID: 39160319
Uromodulin (also known as Tamm-Horsfall protein) is a kidney-specific glycoprotein secreted bidirectionally into urine and into the circulation, and it is the most abundant protein in normal urine. Although the...