Taranjit S Gujral
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Explore the profile of Taranjit S Gujral including associated specialties, affiliations and a list of published articles.
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54
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Recent Articles
11.
Ma R, Tsai P, Farghli A, Shumway A, Kanke M, Gordan J, et al.
PLoS Genet
. 2024 Mar;
20(3):e1011216.
PMID: 38512964
Fibrolamellar carcinoma (FLC) is a rare liver cancer that disproportionately affects adolescents and young adults. Currently, no standard of care is available and there remains a dire need for new...
12.
Chan M, Kang Y, Osborne S, Zager M, Gujral T
Elife
. 2024 Feb;
12.
PMID: 38305363
Cytokines and chemokines are secreted proteins that regulate various biological processes, such as inflammation, immune response, and cell differentiation. Therefore, disruption of signaling pathways involving these proteins has been linked...
13.
Huang Y, Dickerson L, Kenerson H, Jiang X, Pillarisetty V, Tian Q, et al.
BME Front
. 2023 Oct;
4:0022.
PMID: 37849667
In the era of personalized oncology, there have been accelerated efforts to develop clinically relevant platforms to test drug sensitivities of individual cancers. An ideal assay will serve as a...
14.
Pang Y, Li Q, Sergi Z, Yu G, Sang X, Kim O, et al.
bioRxiv
. 2023 Oct;
PMID: 37786680
Highlights: Zotiraciclib (ZTR), a CDK9 inhibitor, hinders IDH-mutant glioma growth and . ZTR halts cell cycle, disrupts respiration, and induces oxidative stress in IDH-mutant cells.ZTR unexpectedly inhibits PIM kinases, impacting...
15.
Olson A, Kang Y, Ladha A, Zhu S, Lim C, Nabet B, et al.
PLoS Pathog
. 2023 Sep;
19(9):e1011169.
PMID: 37669313
Kaposi's sarcoma-associated herpesvirus (KSHV) causes several human diseases including Kaposi's sarcoma (KS), a leading cause of cancer in Africa and in patients with AIDS. KS tumor cells harbor KSHV predominantly...
16.
Friese M, Gujral T, Palanisamy A, Hemmer B, Culley D, Crosby G
Front Aging Neurosci
. 2023 Jun;
15:1060186.
PMID: 37261265
Introduction: The development and maintenance of neural circuits is highly sensitive to neural activity. General anesthetics have profound effects on neural activity and, as such, there is concern that these...
17.
Mossa F, Robesti D, Sumankalai R, Corey E, Titus M, Kang Y, et al.
Mol Cancer Res
. 2022 Sep;
21(1):51-61.
PMID: 36112348
Implications: These vulnerabilities may be exploited with mechanistically novel treatments, such as those targeting OXPHOS alone or possibly in combination with existing therapies. In addition, our findings underscore the impact...
18.
Szulzewsky F, Arora S, Arakaki A, Sievers P, Almiron Bonnin D, Paddison P, et al.
Genes Dev
. 2022 Aug;
PMID: 36008139
YAP1 is a transcriptional coactivator regulated by the Hippo signaling pathway, including NF2. Meningiomas are the most common primary brain tumors; a large percentage exhibit heterozygous loss of chromosome 22...
19.
Sullivan K, Jiang X, Guha P, Lausted C, Carter J, Hsu C, et al.
Gut
. 2022 Jun;
72(2):325-337.
PMID: 35705369
Objective: Programmed cell death protein 1 (PD-1) checkpoint inhibition and adoptive cellular therapy have had limited success in patients with microsatellite stable colorectal cancer liver metastases (CRLM). We sought to...
20.
Chan M, Holland E, Gujral T
EMBO Mol Med
. 2022 May;
14(6):e15919.
PMID: 35579119
The N-terminus domain (NTD) of the SARS-CoV-2 Omicron variant spike protien strongly induces multiple inflammatory molecules in human peripheral blood mononuclear cells, unaffected by the mutations observed in the NTD....