Tanvir Khaliq
Overview
Explore the profile of Tanvir Khaliq including associated specialties, affiliations and a list of published articles.
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15
Citations
143
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Recent Articles
1.
Scherrer K, Eans S, Medina J, Senadheera S, Khaliq T, Murray T, et al.
Pharmaceuticals (Basel)
. 2023 Sep;
16(9).
PMID: 37765026
The macrocyclic tetrapeptide CJ-15,208 ([Phe-D-Pro-Phe-Trp]) and its D-Trp isomer exhibit kappa opioid receptor (KOR) antagonism which prevents stress-induced reinstatement of extinguished cocaine-conditioned place preference. Here, we evaluated the effects of...
2.
Brice-Tutt A, Senadheera S, Ganno M, Eans S, Khaliq T, Murray T, et al.
Molecules
. 2020 Sep;
25(17).
PMID: 32887303
The macrocyclic tetrapeptide [Phe-d-Pro-Phe-Trp] (CJ-15,208) and its stereoisomer [Phe-d-Pro-Phe-d-Trp] exhibit different opioid activity profiles in vivo. The present study evaluated the influence of the Phe residues' stereochemistry on the peptides'...
3.
Khaliq T, Williams T, Senadheera S, Aldrich J
J Chromatogr B Analyt Technol Biomed Life Sci
. 2016 Jun;
1028:11-15.
PMID: 27318293
Selective kappa opioid receptor (KOR) antagonists may have therapeutic potential as treatments for substance abuse and mood disorders. Since [D-Trp]CJ-15,208 (cyclo[Phe-d-Pro-Phe-d-Trp]) is a novel potent KOR antagonist in vivo, it...
4.
Shivahare R, Korthikunta V, Chandasana H, Suthar M, Agnihotri P, Vishwakarma P, et al.
J Med Chem
. 2014 Mar;
57(8):3342-57.
PMID: 24635539
Antileishmanial activities of a library of synthetic chalcone analogues have been examined. Among them, five compounds (11, 14, 16, 17, 22, and 24) exhibited better activity than the marketed drug...
5.
Singh V, Mishra V, Tiwari S, Khaliq T, Barthwal M, Pandey H, et al.
Phytomedicine
. 2013 Jul;
20(13):1180-5.
PMID: 23880327
Gastroprotective mechanism of peganine hydrochloride isolated from Peganum harmala seeds was investigated. Peganine hydrochloride was evaluated against cold restraint (CRU), aspirin (AS), alcohol (AL) and pyloric ligation (PL) induced gastric...
6.
Tadigoppula N, Korthikunta V, Gupta S, Kancharla P, Khaliq T, Soni A, et al.
J Med Chem
. 2012 Dec;
56(1):31-45.
PMID: 23270565
Licochalcone A (I), isolated from the roots of Chinese licorice, is the most promising antimalarial compound reported so far. In continuation of our drug discovery program, we isolated two similar...
7.
Khaliq T, Sadilek M, Scott C, Turecek F, Gelb M
Clin Chem
. 2010 Oct;
57(1):128-31.
PMID: 21030685
Background: Treatments are being developed for an increasing number of mucopolysaccharidoses, and early diagnosis is expected to be necessary to maximize the benefits of therapy. Therefore, we developed an assay...
8.
Duffey T, Khaliq T, Scott C, Turecek F, Gelb M
Bioorg Med Chem Lett
. 2010 Sep;
20(20):5994-6.
PMID: 20833037
In continued efforts to develop enzymatic assays for lysosomal storage diseases appropriate for newborn screening laboratories we have synthesized novel and specific enzyme substrates for Maroteaux-Lamy (MPS VI) and Morquio...
9.
Khaliq T, Misra P, Gupta S, Reddy K, Kant R, Maulik P, et al.
Bioorg Med Chem Lett
. 2009 Apr;
19(9):2585-6.
PMID: 19339182
Protozoic infections caused by genus Leishmania pose an enormous public health threat in developing countries, compounded by the toxicity and resistance to current therapies. Under the aegis of our ongoing...
10.
Misra P, Khaliq T, Dixit A, Sengupta S, Samant M, Kumari S, et al.
J Antimicrob Chemother
. 2008 Aug;
62(5):998-1002.
PMID: 18694906
Objectives: The aim of this study was to resolve the putative pathway responsible for death induced by peganine hydrochloride dihydrate isolated from Peganum harmala seeds at cellular, structural and molecular...