Taneli Heikkinen
Overview
Explore the profile of Taneli Heikkinen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
19
Citations
557
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lehtimaki K, Rytkonen J, Pussinen R, Shatillo A, Bragge T, Heikkinen T, et al.
J Physiol
. 2024 Oct;
602(20):5353-5373.
PMID: 39365978
A significant fraction of the popular inbred C57Bl/6J mice show structural and biochemical features of the congenital portosystemic shunt (PSS). How this hepatic abnormality affects physiological and behavioural parameters has...
2.
Ott K, Heikkinen T, Lehtimaki K, Paldanius K, Puolivali J, Pussinen R, et al.
Front Neurosci
. 2023 Jun;
17:1183023.
PMID: 37325043
Introduction: Cognitive impairment associated with old age or various brain disorders may be very disabling for affected individuals, placing their carers and public health services under considerable stress. The standard-of-care...
3.
Yu-Taeger L, Novati A, Weber J, Singer-Mikosch E, Pabst A, Cheng F, et al.
Cells
. 2022 Dec;
11(23).
PMID: 36497038
Body weight (BW) loss and reduced body mass index (BMI) are the most common peripheral alterations in Huntington disease (HD) and have been found in HD mutation carriers and HD...
4.
Heikkinen T, Bragge T, Kuosmanen J, Parkkari T, Gustafsson S, Kwan M, et al.
PLoS One
. 2021 Oct;
16(10):e0258486.
PMID: 34648564
Huntington's disease (HD) results from an expansion mutation in the polyglutamine tract in huntingtin. Although huntingtin is ubiquitously expressed in the body, the striatum suffers the most severe pathology. Rhes...
5.
Heikkinen T, Bragge T, Bhattarai N, Parkkari T, Puolivali J, Kontkanen O, et al.
PLoS One
. 2020 Dec;
15(12):e0243052.
PMID: 33370315
Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by severe disruption of cognitive and motor functions, including changes in posture and gait. A number of HD mouse models have...
6.
Zeitler B, Froelich S, Marlen K, Shivak D, Yu Q, Li D, et al.
Nat Med
. 2019 Jul;
25(7):1131-1142.
PMID: 31263285
Huntington's disease (HD) is a dominantly inherited neurodegenerative disorder caused by a CAG trinucleotide expansion in the huntingtin gene (HTT), which codes for the pathologic mutant HTT (mHTT) protein. Since...
7.
Piiponniemi T, Parkkari T, Heikkinen T, Puolivali J, Park L, Cachope R, et al.
Front Behav Neurosci
. 2018 Oct;
12:226.
PMID: 30333735
Cognitive disturbances often predate characteristic motor dysfunction in individuals with Huntington's disease (HD) and place an increasing burden on the HD patients and caregivers with the progression of the disorder....
8.
Datson N, Gonzalez-Barriga A, Kourkouta E, Weij R, van de Giessen J, Mulders S, et al.
PLoS One
. 2017 Feb;
12(2):e0171127.
PMID: 28182673
The aim of these studies was to demonstrate the therapeutic capacity of an antisense oligonucleotide with the sequence (CUG)7 targeting the expanded CAG repeat in huntingtin (HTT) mRNA in vivo...
9.
Beaumont V, Zhong S, Lin H, Xu W, Bradaia A, Steidl E, et al.
Neuron
. 2016 Dec;
92(6):1220-1237.
PMID: 27916455
Huntington's disease (HD) symptoms are driven to a large extent by dysfunction of the basal ganglia circuitry. HD patients exhibit reduced striatal phoshodiesterase 10 (PDE10) levels. Using HD mouse models...
10.
Beaumont V, Mrzljak L, Dijkman U, Freije R, Heins M, Rassoulpour A, et al.
Exp Neurol
. 2016 May;
282:99-118.
PMID: 27163548
Dysregulation of the kynurenine (Kyn) pathway has been associated with the progression of Huntington's disease (HD). In particular, elevated levels of the kynurenine metabolites 3-hydroxy kynurenine (3-OH-Kyn) and quinolinic acid...