Raimo Pussinen
Overview
Explore the profile of Raimo Pussinen including associated specialties, affiliations and a list of published articles.
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8
Citations
71
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0
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Recent Articles
1.
Lehtimaki K, Rytkonen J, Pussinen R, Shatillo A, Bragge T, Heikkinen T, et al.
J Physiol
. 2024 Oct;
602(20):5353-5373.
PMID: 39365978
A significant fraction of the popular inbred C57Bl/6J mice show structural and biochemical features of the congenital portosystemic shunt (PSS). How this hepatic abnormality affects physiological and behavioural parameters has...
2.
Ott K, Heikkinen T, Lehtimaki K, Paldanius K, Puolivali J, Pussinen R, et al.
Front Neurosci
. 2023 Jun;
17:1183023.
PMID: 37325043
Introduction: Cognitive impairment associated with old age or various brain disorders may be very disabling for affected individuals, placing their carers and public health services under considerable stress. The standard-of-care...
3.
Puolivali J, Nurmi A, Miettinen T, Soleti A, Riccardino F, Kalesnykas G, et al.
J Alzheimers Dis
. 2011 Aug;
27(3):499-510.
PMID: 21821875
The purpose of this study was to evaluate the efficacy of the radical scavenger IAC (bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl) decantionate) in alleviating behavioral deficits and reducing amyloid-β (Aβ) accumulation in an Alzheimer's disease...
4.
Nurmi A, Miettinen T, Puolivali J, Pussinen R, Soleti A, Bagate K, et al.
Brain Res
. 2008 Apr;
1207:174-81.
PMID: 18374313
Experimental evidence suggests that reactive free radicals are generated during brain ischemia. We investigated the effect of a novel brain penetrant, low molecular weight, non-peptidyl carbon, oxygen- and nitrogen-centered radical...
5.
Siiskonen H, Oikari S, Korhonen V, Pitkanen A, Voikar V, Kettunen M, et al.
Mol Cell Neurosci
. 2006 Dec;
34(2):199-208.
PMID: 17150371
Diazepam binding inhibitor (DBI) and its processing products are endogenous modulators of GABAA and linked to various brain disorders ranging from anxiety and drug dependence to epilepsy. To investigate the...
6.
Malm T, Ort M, Tahtivaara L, Jukarainen N, Goldsteins G, Puolivali J, et al.
Proc Natl Acad Sci U S A
. 2006 May;
103(23):8852-7.
PMID: 16723396
beta-Amyloid (Abeta) polypeptide plays a critical role in the pathogenesis of Alzheimer's disease (AD), which is characterized by progressive decline of cognitive functions, formation of Abeta deposits and neurofibrillary tangles,...
7.
Karhunen H, Pitkanen A, Virtanen T, Gureviciene I, Pussinen R, Ylinen A, et al.
Epilepsy Res
. 2003 May;
54(1):1-10.
PMID: 12742590
Post-stroke seizures occur in 5-20% of patients. Modeling of stroke-induced seizures in animals provides a useful tool for investigating the molecular basis of epileptogenesis and for developing therapies for stroke...
8.
Gureviciene I, Puolivali J, Pussinen R, Wang J, Tanila H, Ylinen A
Neurobiol Learn Mem
. 2002 Dec;
79(1):72-80.
PMID: 12482681
Estrogen is implicated in hippocampus-dependent spatial learning as well as structural organization and electrophysiological properties of the rat hippocampus but little is known about its mechanisms of action in mice....