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Tamio Furuse

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Articles 31
Citations 324
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Recent Articles
1.
Hagihara H, Shoji H, Hattori S, Sala G, Takamiya Y, Tanaka M, et al.
Elife . 2024 Mar; 12. PMID: 38529532
Increased levels of lactate, an end-product of glycolysis, have been proposed as a potential surrogate marker for metabolic changes during neuronal excitation. These changes in lactate levels can result in...
2.
Yamada M, Nitta Y, Uehara T, Suzuki H, Miya F, Takenouchi T, et al.
Eur J Med Genet . 2023 Jun; 66(8):104804. PMID: 37369308
DExH-box helicases are involved in unwinding of RNA and DNA. Among the 16 DExH-box genes, monoallelic variants of DHX16, DHX30, DHX34, and DHX37 are known to be associated with neurodevelopmental...
3.
Sato Y, Tsuyusaki M, Takahashi-Iwanaga H, Fujisawa R, Masamune A, Hamada S, et al.
Front Mol Biosci . 2022 Nov; 9:1040237. PMID: 36419930
The type 2 Ca-dependent activator protein for secretion (CAPS2/CADPS2) regulates dense-core vesicle trafficking and exocytosis and is involved in the regulated release of catecholamines, peptidergic hormones, and neuromodulators. CAPS2 is...
4.
Uemura M, Furuse T, Yamada I, Kushida T, Abe T, Imai K, et al.
Sci Rep . 2022 Jul; 12(1):11933. PMID: 35831353
Protocadherin 9 (Pcdh9) is a member of the cadherin superfamily and is uniquely expressed in the vestibular and limbic systems; however, its physiological role remains unclear. Here, we studied the...
5.
Hirata T, Kobayashi A, Furuse T, Yamada I, Tamura M, Tomita H, et al.
J Biol Chem . 2022 Feb; 298(3):101720. PMID: 35151686
Glycosylphosphatidylinositol (GPI) is a posttranslational glycolipid modification of proteins that anchors proteins in lipid rafts on the cell surface. Although some GPI-anchored proteins (GPI-APs), including the prion protein PrP, have...
6.
Zhang C, Clough S, Adamah-Biassi E, Sveinsson M, Hutchinson A, Miura I, et al.
J Pineal Res . 2021 Jun; 71(2):e12748. PMID: 34085306
The hormone melatonin is synthesized from serotonin by two enzymatic reactions (AANAT and ASMT/HIOMT) in the pineal gland following a circadian rhythm with low levels during the day and high...
7.
Horiai M, Otsuka A, Hidema S, Hiraoka Y, Hayashi R, Miyazaki S, et al.
Sci Rep . 2020 Dec; 10(1):22173. PMID: 33335150
Autism spectrum disorder (ASD) is a continuum of neurodevelopmental disorders and needs new therapeutic approaches. Recently, oxytocin (OXT) showed potential as the first anti-ASD drug. Many reports have described the...
8.
Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, et al.
Nat Commun . 2020 Feb; 11(1):859. PMID: 32103003
Pogo transposable element derived with ZNF domain (POGZ) has been identified as one of the most recurrently de novo mutated genes in patients with neurodevelopmental disorders (NDDs), including autism spectrum...
9.
Furuse T, Mizuma H, Hirose Y, Kushida T, Yamada I, Miura I, et al.
Dis Model Mech . 2019 Aug; 12(9). PMID: 31399478
Dysfunction of glucose transporter 1 (GLUT1) proteins causes infantile epilepsy, which is designated as a GLUT1 deficiency syndrome (GLUT1DS; OMIM #606777). Patients with GLUT1DS display varied clinical phenotypes, such as...
10.
Kim K, Suzuki A, Kojima H, Kawamura M, Miya K, Abe M, et al.
Neurobiol Learn Mem . 2018 Dec; 157:86-95. PMID: 30528771
CaMKII is a pivotal kinase that plays essential roles in synaptic plasticity. Apart from its signaling function, the structural function of CaMKII is becoming clear. CaMKII - F-actin interaction stabilizes...