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Tamara Vital

Explore the profile of Tamara Vital including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 43
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Recent Articles
1.
Vital T, Wali A, Butler K, Xiong Y, Foster 2nd J, Marcel S, et al.
Front Oncol . 2023 Feb; 13:1099550. PMID: 36793594
Ewing sarcoma is a cancer of children and young adults characterized by the critical translocation-associated fusion oncoprotein EWSR1::FLI1. EWSR1::FLI1 targets characteristic genetic loci where it mediates aberrant chromatin and the...
2.
Su S, Chen J, Jiang Y, Wang Y, Vital T, Zhang J, et al.
Adv Sci (Weinh) . 2021 Jun; 8(14):e2004846. PMID: 34060252
Chromosomal translocation results in development of an Ewing sarcoma breakpoint region 1-Friend leukemia integration 1 (EWS-FLI1) fusion oncogene in the majority of Ewing sarcoma. The persistent dependence of the tumor...
3.
Chou D, Vetere A, Choudhary A, Scully S, Schenone M, Tang A, et al.
J Am Chem Soc . 2015 Jun; 137(24):7929-34. PMID: 26042473
Phenotypic cell-based screening is a powerful approach to small-molecule discovery, but a major challenge of this strategy lies in determining the intracellular target and mechanism of action (MoA) for validated...