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Tamar Ziv

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Articles 94
Citations 1986
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Recent Articles
1.
Qarawani A, Naaman E, Ben-Zvi Elimelech R, Harel M, Sigal-Dror S, Ben-Zur T, et al.
J Extracell Biol . 2025 Jan; 4(1):e70024. PMID: 39844926
Amyloid β (Aβ) has emerged as a pathophysiological driver in age-related macular degeneration (AMD), emphasizing its significance in the aetiology of this prevalent sight-threatening condition. The multifaceted nature of AMD...
2.
Gottfried Y, Lulu-Shimron C, Goldhirsh G, Fisher Y, Ziv T, Hoon D, et al.
Biochem Biophys Res Commun . 2024 Dec; 745:151231. PMID: 39732122
The ubiquitin proteasome system (UPS), driven by ubiquitin as a degradation signal, eliminates, in a highly specific manner, 'abnormal' proteins and proteins that completed their function. This process involves a...
3.
Fu A, Luo Z, Ziv T, Bi X, Lulu-Shimron C, Cohen-Kaplan V, et al.
Proc Natl Acad Sci U S A . 2024 Oct; 121(43):e2414377121. PMID: 39418304
Liquid-liquid phase separation has emerged as a crucial mechanism driving the formation of membraneless biomolecular condensates, which play important roles in numerous cellular processes. These condensates, found both in the...
4.
Livneh I, Fabre B, Goldhirsh G, Lulu C, Zinger A, Shammai Vainer Y, et al.
Cell Death Differ . 2024 Sep; 31(10):1242-1254. PMID: 39266717
The proteasome, the catalytic arm of the ubiquitin system, is regulated via its dynamic compartmentation between the nucleus and the cytoplasm, among other mechanisms. Under amino acid shortage, the proteolytic...
5.
Haddad R, Sadeh O, Ziv T, Erlich I, Haimovich-Caspi L, Shemesh A, et al.
J Clin Invest . 2024 May; 134(13). PMID: 38743494
Cardiomyocyte sarcomeres contain localized ribosomes, but the factors responsible for their localization and the significance of localized translation are unknown. Using proximity labeling, we identified ribosomal protein SA (RPSA) as...
6.
Salti T, Braunstein I, Haimovich Y, Ziv T, Benhar M
Redox Biol . 2024 Apr; 72:103125. PMID: 38574432
Acute inflammatory responses often involve the production of reactive oxygen and nitrogen species by innate immune cells, particularly macrophages. How activated macrophages protect themselves in the face of oxidative-inflammatory stress...
7.
Kaplan B, Goldis R, Ziv T, Dori A, Magen H, Simon A, et al.
Isr Med Assoc J . 2024 Mar; 26(3):149-156. PMID: 38493325
Background: Cardiac amyloidosis (CA) is characterized by the extracellular deposition of misfolded protein in the heart. Precise identification of the amyloid type is often challenging, but critical, since the treatment...
8.
Nadel G, Yao Z, Hacohen-Lev-Ran A, Wainstein E, Maik-Rachline G, Ziv T, et al.
Cell Commun Signal . 2024 Feb; 22(1):154. PMID: 38419089
Background: Although GqPCR activation often leads to cell survival by activating the PI3K/AKT pathway, it was previously shown that in several cell types AKT activity is reduced and leads to...
9.
Shakarchy A, Zarfati G, Hazak A, Mealem R, Huk K, Ziv T, et al.
Mol Syst Biol . 2024 Jan; 20(3):217-241. PMID: 38238594
Cells modify their internal organization during continuous state transitions, supporting functions from cell division to differentiation. However, tools to measure dynamic physiological states of individual transitioning cells are lacking. We...
10.
Goldis R, Kaplan B, Arad M, Dispenzieri A, Dasari S, Kukuy O, et al.
Clin Chem Lab Med . 2023 Sep; 62(3):464-471. PMID: 37747270
Objectives: Diagnosis of light chain amyloidosis (AL) requires demonstration of amyloid deposits in a tissue biopsy followed by appropriate typing. Previous studies demonstrated increased dimerization of monoclonal serum free light...