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Tam-Hao T Phan

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Articles 23
Citations 394
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Recent Articles
1.
Qian J, Mummalaneni S, Phan T, Heck G, DeSimone J, West D, et al.
PLoS One . 2017 Feb; 12(2):e0171335. PMID: 28192441
During postnatal development rats demonstrate an age-dependent increase in NaCl chorda tympani (CT) responses and the number of functional apical amiloride-sensitive epithelial Na+ channels (ENaCs) in salt sensing fungiform (FF)...
2.
DeSimone J, Phan T, Mummalaneni S, Rhyu M, Heck G, Lyall V
Chem Senses . 2015 May; 40(6):401-12. PMID: 25953775
Modulatory effects of pHi and [Ca(2+)]i on taste receptor cell (TRC) epithelial sodium channel (ENaC) were investigated by monitoring chorda tympani (CT) responses to NaCl and KCl at various lingual...
3.
Mummalaneni S, Qian J, Phan T, Rhyu M, Heck G, DeSimone J, et al.
PLoS One . 2014 May; 9(5):e98049. PMID: 24839965
The effects of small molecule ENaC activators N,N,N-trimethyl-2-((4-methyl-2-((4-methyl-1H-indol-3-yl)thio)pentanoyl)oxy)ethanaminium iodide (Compound 1) and N-(2-hydroxyethyl)-4-methyl-2-((4-methyl-1H-indol-3-yl)thio)pentanamide (Compound 2), were tested on the benzamil (Bz)-sensitive NaCl chorda tympani (CT) taste nerve response under open-circuit...
4.
Ren Z, Rhyu M, Phan T, Mummalaneni S, Murthy K, Grider J, et al.
Am J Physiol Gastrointest Liver Physiol . 2013 May; 305(1):G106-17. PMID: 23639808
Transient receptor potential (TRP) subfamily M member 5 (TRPM5) cation channel is involved in sensing sweet, bitter, umami, and fat taste stimuli, complex-tasting divalent salts, and temperature-induced changes in sweet...
5.
Dewis M, Phan T, Ren Z, Meng X, Cui M, Mummalaneni S, et al.
J Neurophysiol . 2012 Dec; 109(4):1078-90. PMID: 23221408
Effects of N-geranyl cyclopropyl-carboxamide (NGCC) and four structurally related compounds (N-cyclopropyl E2,Z6-nonadienamide, N-geranyl isobutanamide, N-geranyl 2-methylbutanamide, and allyl N-geranyl carbamate) were evaluated on the chorda tympani (CT) nerve response to...
6.
DeSimone J, Phan T, Ren Z, Mummalaneni S, Lyall V
J Neurophysiol . 2012 Sep; 108(12):3221-32. PMID: 22993258
The relationship between taste receptor cell (TRC) intracellular Ca(2+) ([Ca(2+)](i)) and rat chorda tympani (CT) nerve responses to bitter (quinine and denatonium), sweet (sucrose, glycine, and erythritol), and umami [monosodium...
7.
DeSimone J, Ren Z, Phan T, Heck G, Mummalaneni S, Lyall V
J Neurophysiol . 2012 Sep; 108(12):3206-20. PMID: 22956787
The relationship between taste receptor cell (TRC) Ca(2+) concentration ([Ca(2+)](i)) and rat chorda tympani (CT) nerve responses to salty [NaCl and NaCl+benzamil (Bz)] and sour (HCl, CO(2), and acetic acid)...
8.
Coleman J, Williams A, Phan T, Mummalaneni S, Melone P, Ren Z, et al.
J Neurophysiol . 2011 Aug; 106(5):2606-21. PMID: 21849614
Strain differences between naive, sucrose- and ethanol-exposed alcohol-preferring (P) and alcohol-nonpreferring (NP) rats were investigated in their consumption of ethanol, sucrose, and NaCl; chorda tympani (CT) nerve responses to sweet...
9.
DeSimone J, Phan T, Heck G, Ren Z, Coleman J, Mummalaneni S, et al.
Chem Senses . 2011 Feb; 36(4):389-403. PMID: 21339339
To investigate if chorda tympani (CT) taste nerve responses to strong (HCl) and weak (CO(2) and acetic acid) acidic stimuli are dependent upon NADPH oxidase-linked and cAMP-sensitive proton conductances in...
10.
Sturz G, Phan T, Mummalaneni S, Ren Z, DeSimone J, Lyall V
Chem Senses . 2011 Jan; 36(4):375-88. PMID: 21257734
The relationship between acidic pH, taste cell pH(i), and chorda tympani (CT) nerve responses was investigated before and after incorporating the K(+)-H(+) exchanger, nigericin, in the apical membrane of taste...