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Tal Yardeni

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Articles 24
Citations 633
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Recent Articles
1.
Passini F, Bornstein B, Rubin S, Kuperman Y, Krief S, Masschelein E, et al.
Cell Metab . 2025 Feb; PMID: 39919739
Systemic metabolism ensures energy homeostasis through inter-organ crosstalk regulating thermogenic adipose tissue. Unlike the well-described inductive role of the sympathetic system, the inhibitory signal ensuring energy preservation remains poorly understood....
2.
Yardeni T, Olali A, Chen H, Wang L, Halton J, Zenab A, et al.
Proc Natl Acad Sci U S A . 2025 Jan; 122(1):e2417252121. PMID: 39752523
Mitochondrial DNA (mtDNA) is highly polymorphic, and host mtDNA variation has been associated with altered cancer severity. To determine the basis of this mtDNA-cancer association, we analyzed conplastic mice with...
3.
Gross G, Alkadieri S, Meir A, Itzhaki O, Aharoni-Tevet Y, Ben Yosef S, et al.
Leukemia . 2024 May; 38(7):1534-1540. PMID: 38714877
CD19 CAR-T cells have led to durable remissions in patients with refractory B-cell malignancies; nevertheless, most patients eventually relapse in the long term. Many interventions aimed at improving current products...
4.
Gross G, Alkadieri S, Meir A, Itzhaki O, Aharony-Tevet Y, Ben Yosef S, et al.
bioRxiv . 2023 Oct; PMID: 37808778
CD19 CAR-T cells have led to durable remissions in patients with refractory B-cell malignancies; nevertheless, most patients eventually relapse in the long term. Many interventions aimed at improving current products...
5.
Schaefer P, Scherer Alves L, Lvova M, Huang J, Rathi K, Janssen K, et al.
Proc Natl Acad Sci U S A . 2022 Nov; 119(45):e2212417119. PMID: 36322731
Mitochondrial dysfunction can be associated with a range of clinical manifestations. Here, we report a family with a complex phenotype including combinations of connective tissue, neurological, and metabolic symptoms that...
6.
Schaefer P, Huang J, Butic A, Perry C, Yardeni T, Tan W, et al.
Mol Metab . 2022 Aug; 64:101560. PMID: 35940554
Objective: Mitochondrial disorders are often characterized by muscle weakness and fatigue. Null mutations in the heart-muscle adenine nucleotide translocator isoform 1 (ANT1) of both humans and mice cause cardiomyopathy and...
7.
Kozicz T, Morava E, Yardeni T
Eur J Neurosci . 2021 Apr; 53(9):2943-2945. PMID: 33861478
No abstract available.
8.
Yardeni T, Cristancho A, McCoy A, Schaefer P, McManus M, Marsh E, et al.
Proc Natl Acad Sci U S A . 2021 Feb; 118(6). PMID: 33536343
Autism spectrum disorders (ASDs) are characterized by a deficit in social communication, pathologic repetitive behaviors, restricted interests, and electroencephalogram (EEG) aberrations. While exhaustive analysis of nuclear DNA (nDNA) variation has...
9.
Huizing M, Yardeni T, Fuentes F, Malicdan M, Leoyklang P, Volkov A, et al.
Kidney Int Rep . 2019 Nov; 4(10):1454-1462. PMID: 31701055
Introduction: Sialic acids are important contributors to the polyanionic component of the glomerular filtration barrier, which regulates permeability selectivity. Pathologic glomerular hyposialylation, associated with podocyte effacement, has been implicated in...
10.
Yardeni T, Tanes C, Bittinger K, Mattei L, Schaefer P, Singh L, et al.
Sci Signal . 2019 Jul; 12(588). PMID: 31266851
Changes in the gut microbiota and the mitochondrial genome are both linked with the development of disease. To investigate why, we examined the gut microbiota of mice harboring various mutations...