Takumi Yokokawa
Overview
Explore the profile of Takumi Yokokawa including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
174
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Recent Articles
1.
CRTC1 in Mc4r-Expressing Cells Is Required for Peripheral Metabolism and Systemic Energy Homeostasis
Miyamori H, Yokokawa T, Miyakita M, Ozaki K, Goto T, Inoue K, et al.
Diabetes
. 2024 Sep;
73(12):1976-1989.
PMID: 39264819
Article Highlights:
2.
Egawa T, Ogawa T, Yokokawa T, Kido K, Iyama R, Zhao H, et al.
J Cachexia Sarcopenia Muscle
. 2024 Apr;
15(3):883-896.
PMID: 38575520
Background: Glycative stress, characterized by the formation and accumulation of advanced glycation end products (AGEs) associated with protein glycation reactions, has been implicated in inducing a decline of muscle function....
3.
Yokokawa T, Kido K, Sato K, Hayashi T, Fujita S
Physiol Rep
. 2023 Apr;
11(8):e15673.
PMID: 37078449
Mounting evidence links Type 1 diabetes (T1D) with cognitive dysfunction, psychiatric disorders, and synaptic alterations; however, the underlying mechanism remains unclear. Numerous synaptic proteins and synaptic adhesion molecules (SAMs) that...
4.
Matsumura S, Miyakita M, Miyamori H, Kyo S, Ishikawa F, Sasaki T, et al.
FASEB J
. 2022 Nov;
36(12):e22645.
PMID: 36349991
Melanocortin-4 receptor (MC4R) is a critical regulator of appetite and energy expenditure in rodents and humans. MC4R deficiency causes hyperphagia, reduced energy expenditure, and impaired glucose metabolism. Ligand binding to...
5.
Yokokawa T, Sasaki S, Sase K, Yoshii N, Yasuda J, Hayashi T, et al.
PLoS One
. 2022 Aug;
17(8):e0273056.
PMID: 35998179
Substantial evidence suggests an important role of liver function in brain health. Liver function is clinically assessed by measuring the activity of hepatic enzymes in the peripheral blood. Brain-derived neurotrophic...
6.
Matsumura S, Miyakita M, Miyamori H, Kyo S, Shima D, Yokokawa T, et al.
Am J Physiol Endocrinol Metab
. 2022 Mar;
322(5):E436-E445.
PMID: 35344393
The melanocortin 4 receptor (MC4R) plays an important role in the regulation of appetite and energy expenditure in humans and rodents. Impairment of MC4R signaling causes severe obesity. MC4R mainly...
7.
Yasuda J, Murata K, Hasegawa T, Yamamura M, Maeo S, Takegaki J, et al.
Nutrition
. 2022 Mar;
97:111607.
PMID: 35231855
Objective: The aim of this study was to observe the relationship of protein intake at each meal and daily total with change in lean tissue mass with progressive resistance exercise...
8.
Fujiyoshi H, Egawa T, Kurogi E, Yokokawa T, Kido K, Hayashi T
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163799
Endurance exercise induces various adaptations that yield health benefits; however, the underlying molecular mechanism has not been fully elucidated. Given that it has recently been accepted that inflammatory responses are...
9.
Egawa T, Ogawa T, Yokokawa T, Kido K, Goto K, Hayashi T
J Appl Physiol (1985)
. 2022 Jan;
132(2):477-488.
PMID: 35023763
Endurance exercise triggers skeletal muscle adaptations, including enhanced insulin signaling, glucose metabolism, and mitochondrial biogenesis. However, exercise-induced skeletal muscle adaptations may not occur in some cases, a condition known as...
10.
Tanaka J, Ishikawa F, Jinno T, Miyakita M, Miyamori H, Sasaki T, et al.
PLoS One
. 2022 Jan;
17(1):e0262577.
PMID: 35020776
cAMP responsive element binding protein (CREB)-regulated transcription coactivators (CRTCs) regulate gene transcription in response to an increase in intracellular cAMP or Ca2+ levels. To date, three isoforms of CRTC have...