Takeshi Ichinohe
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Explore the profile of Takeshi Ichinohe including associated specialties, affiliations and a list of published articles.
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54
Citations
3742
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Recent Articles
1.
Kobayashi M, Kobayashi N, Deguchi K, Omori S, Ichinohe T
NPJ Vaccines
. 2025 Feb;
10(1):40.
PMID: 40016252
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is constantly evolving mutations in the Spike protein to evade humoral immunity. Respiratory tract antiviral IgA antibodies are superior to circulating IgG antibodies...
2.
Yang J, Song I, Saito M, Hartanto T, Ichinohe T, Fukuda S
Gut Microbiome (Camb)
. 2025 Feb;
6:e1.
PMID: 39944118
The coronavirus disease 2019 (COVID-19) pandemic has caused health issues worldwide. Studies have suggested that modulation of the gut microbiota could attenuate the severity of COVID-19 symptoms. In light of...
3.
Yano S, Asami N, Kishi Y, Takeda I, Kubotani H, Hattori Y, et al.
Nat Neurosci
. 2025 Jan;
28(3):487-498.
PMID: 39825140
Microglia-resident immune cells in the central nervous system-undergo morphological and functional changes in response to signals from the local environment and mature into various homeostatic states. However, niche signals underlying...
4.
Kobayashi M, Kobayashi N, Deguchi K, Omori S, Nagai M, Fukui R, et al.
PLoS Pathog
. 2024 Dec;
20(12):e1012776.
PMID: 39652608
Since most genetically modified mice are C57BL/6 background, a mouse-adapted SARS-CoV-2 that causes lethal infection in young C57BL/6 mice is useful for studying innate immune protection against SARS-CoV-2 infection. Here,...
5.
Song I, Yang J, Saito M, Hartanto T, Nakayama Y, Ichinohe T, et al.
NPJ Sci Food
. 2024 Mar;
8(1):18.
PMID: 38485724
Current treatment options for COVID-19 are limited, with many antivirals and immunomodulators restricted to the most severe cases and preventative care limited to vaccination. As the SARS-CoV-2 virus and its...
6.
Shibata T, Sato R, Taoka M, Saitoh S, Komine M, Yamaguchi K, et al.
J Exp Med
. 2023 Jul;
220(9).
PMID: 37462944
Loss-of-function mutations in the lysosomal nucleoside transporter SLC29A3 cause lysosomal nucleoside storage and histiocytosis: phagocyte accumulation in multiple organs. However, little is known about the mechanism by which lysosomal nucleoside...
7.
Nagai M, Moriyama M, Ishii C, Mori H, Watanabe H, Nakahara T, et al.
Nat Commun
. 2023 Jun;
14(1):3863.
PMID: 37391427
Fever is a common symptom of influenza and coronavirus disease 2019 (COVID-19), yet its physiological role in host resistance to viral infection remains less clear. Here, we demonstrate that exposure...
8.
Tatsuma T, Nakakido M, Ichinohe T, Kuroiwa Y, Tomioka K, Liu C, et al.
Sci Rep
. 2023 Mar;
13(1):4033.
PMID: 36899059
In order to reduce infection risk of novel coronavirus (SARS-CoV-2), we developed nano-photocatalysts with nanoscale rutile TiO (4-8 nm) and CuO (1-2 nm or less). Their extraordinarily small size leads...
9.
Nagai M, Moriyama M, Ichinohe T
mBio
. 2021 Aug;
12(4):e0159821.
PMID: 34399617
The gut microbiota plays a critical role in the induction of adaptive immune responses to influenza virus infection. However, the role of nasal bacteria in the induction of the virus-specific...
10.
Liu K, Sato R, Shibata T, Hiranuma R, Reuter T, Fukui R, et al.
Int Immunol
. 2021 Jun;
33(9):479-490.
PMID: 34161582
RNase T2, a ubiquitously expressed RNase, degrades RNAs in the endosomal compartments. RNA sensors, double-stranded RNA (dsRNA)-sensing Toll-like receptor 3 (TLR3) and single-stranded RNA (ssRNA)-sensing TLR7, are localized in the...