Takashi Ohtsuki
Overview
Explore the profile of Takashi Ohtsuki including associated specialties, affiliations and a list of published articles.
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Articles
170
Citations
1400
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0
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Recent Articles
1.
Naniwa S, Nishida K, Yoshida A, Nasu Y, Nakahara R, Ohtsuki T, et al.
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39940775
We investigated the roles of low-density lipoprotein receptor-related protein (LRP) 4 and its ligand Agrin in the pathophysiology of cartilage degeneration. Immunohistochemical analysis of human normal articular cartilage and cartilage...
2.
Fithroni A, Inoue H, Zhou S, Hakim T, Tada T, Suzuki M, et al.
Cells
. 2025 Jan;
14(1.
PMID: 39791761
Boron (B) neutron capture therapy (BNCT) is a novel non-invasive targeted cancer therapy based on the nuclear capture reaction B (n, alpha) Li that enables the death of cancer cells...
3.
Ohtsuki T, Sato I, Takashita R, Kodama S, Ikemura K, Opoku G, et al.
Int J Mol Sci
. 2024 Nov;
25(22).
PMID: 39596012
Osteoarthritis (OA) is a chronic disease affecting over 500 million people worldwide. As the population ages and obesity rates rise, the societal burden of OA is increasing. Pro-inflammatory cytokines, particularly...
4.
Murayama K, Ohtsuki T
Biochem Biophys Res Commun
. 2024 Sep;
733:150704.
PMID: 39293335
Botryococcus braunii is a colonial alga recognized for its slow growth but high hydrocarbon accumulation. Although using genetic engineering to increase the growth rate and hydrocarbon yield of B. braunii...
5.
Zhou S, Nishimura F, Wada K, Fujii K, Kondo T, Watanabe K, et al.
Bioorg Med Chem Lett
. 2024 Aug;
112:129915.
PMID: 39127242
Many reports have shown that stabilization of secondary structure by stapling functional peptides enhances the intracellular bioactivity. However, no report has discussed the correlation between stabilization and biological activity based...
6.
Ohtsuki T, Huang Y, Kamiya A, Nakayama Y, Matsushita M, Morikawa S, et al.
J Pharm Health Care Sci
. 2024 Jul;
10(1):35.
PMID: 38970102
We developed a reliable high-performance liquid chromatographic analysis method using a relative molar sensitivity (RMS) technique that does not require an authentic, identical reference analyte material to quantify blood serum...
7.
Zhou S, Tsutsumiuchi K, Imai R, Miki Y, Kondo A, Nakagawa H, et al.
Molecules
. 2024 Jun;
29(11).
PMID: 38893510
Cancer cells have higher heat sensitivity compared to normal cells; therefore, hyperthermia is a promising approach for cancer therapy because of its ability to selectively kill cancer cells by heating...
8.
Murayama K, Ohtsuki T
J Microbiol Methods
. 2023 Nov;
216:106859.
PMID: 37995829
Botryococcus braunii, a colonial alga, is known for notably slow growth; however, the growth rate and hydrocarbon productivity are expected to be improved using genetic modification techniques. Nevertheless, B. braunii...
9.
Ikawa Y, Wakai T, Funahashi H, Soe T, Watanabe K, Ohtsuki T
Sci Rep
. 2023 Aug;
13(1):13050.
PMID: 37567923
Single-cell-specific delivery of small RNAs, such as short hairpin RNA (shRNA) and small noncoding RNAs, allows us to elucidate the roles of specific upregulation of RNA expression and RNAi-mediated gene...
10.
Fuji Y, Uchida K, Akashi T, Ohtsuki T, Matsufuji H, Hirai M
Plant Cell Physiol
. 2023 May;
64(7):716-728.
PMID: 37233612
Sesame (Sesamum indicum L.) plants contain large amounts of acteoside, a typical phenylethanoid glycoside (PhG) that exhibits various pharmacological activities. Although there is increasing interest in the biosynthesis of PhGs...