Hiroki Mizukami
Overview
Explore the profile of Hiroki Mizukami including associated specialties, affiliations and a list of published articles.
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Articles
144
Citations
2604
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Recent Articles
1.
Amo-Shiinoki K, Tanabe K, Nishimura W, Hatanaka M, Kondo M, Kagawa S, et al.
Sci Transl Med
. 2025 Feb;
17(786):eadp2332.
PMID: 39970233
Insulin-dependent diabetes in patients with Wolfram syndrome (WS; OMIM 222300) has been linked to endoplasmic reticulum (ER) stress caused by gene mutations. However, the pathological process of ER stress-associated β...
2.
Wang Z, Kushibiki H, Tarusawa T, Osonoi S, Ogasawara S, Miura C, et al.
J Neurochem
. 2024 Oct;
169(2):e16235.
PMID: 39453752
Diabetic polyneuropathy (DPN) is a multifactorial disease associated not only with hyperglycaemia but also with circulatory disturbances such as hypertension. A close interaction between the immune system and hypertension is...
3.
Ryuzaki M, Mizukami H, Takeuchi Y, Osonoi S, Sasaki T, Wang Z, et al.
Nutr Neurosci
. 2024 Jul;
:1-11.
PMID: 39052592
Introduction: Small fibre neuropathy (SFN) is an early manifestation of diabetic polyneuropathy. Although oxidative stress, inflammation and change of intestinal bacterial population are assumed to be their pathogenesis, the effects...
4.
Mizukami H
Pathol Int
. 2024 Jun;
74(8):438-453.
PMID: 38888200
Currently, there are more than 10 million patients with diabetes mellitus in Japan. Therefore, the need to explore the pathogenesis of diabetes and the complications leading to its cure is...
5.
Pereye O, Nakagawa Y, Sato T, Fukunaka A, Aoyama S, Nishida Y, et al.
J Pathol
. 2024 Jun;
263(4-5):429-441.
PMID: 38837231
The Ppy gene encodes pancreatic polypeptide (PP) secreted by PP- or γ-cells, which are a subtype of endocrine cells localised mainly in the islet periphery. For a detailed characterisation of...
6.
Kushibiki H, Mizukami H, Osonoi S, Takeuchi Y, Sasaki T, Ogasawara S, et al.
Brain Commun
. 2024 Apr;
6(2):fcae103.
PMID: 38618209
Small nerve fibres located in the epidermis sense pain. Dysfunction of these fibres decreases the pain threshold known as small fibre neuropathy. Diabetes mellitus is accompanied by metabolic changes other...
7.
Matsumoto M, Rokunohe D, Sasaki T, Matsuzaki Y, Nakano H, Mizukami H, et al.
Exp Ther Med
. 2024 Apr;
27(5):228.
PMID: 38596658
Glucose transporter isoform 1 (GLUT1), which is upregulated in a variety of malignant tumors, facilitates cellular glucose uptake to boost rapid tumor growth and progression. In several types of cancer,...
8.
Midorikawa S, Mizukami H, Kudoh K, Takeuchi Y, Sasaki T, Kushibiki H, et al.
Pathology
. 2023 Dec;
56(1):65-74.
PMID: 38071160
Epstein‒Barr virus (EBV) infection is a primary oncogenic factor of nasopharyngeal carcinoma (NPC) that elicits epithelial-mesenchymal transition (EMT). Although diabetic patients are more susceptible to various infectious diseases, the pathological...
9.
Kasai S, Kokubu D, Mizukami H, Itoh K
Biomolecules
. 2023 Oct;
13(10).
PMID: 37892226
Reactive oxygen species (ROS) are produced mainly by mitochondrial respiration and function as signaling molecules in the physiological range. However, ROS production is also associated with the pathogenesis of various...
10.