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Taitea Dykstra

Explore the profile of Taitea Dykstra including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 1137
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Recent Articles
1.
Kim M, Gao W, Lichti C, Gu X, Dykstra T, Cao J, et al.
Nature . 2024 Oct; 637(8044):176-183. PMID: 39476864
Despite the presence of strategically positioned anatomical barriers designed to protect the central nervous system (CNS), it is not entirely isolated from the immune system. In fact, it remains physically...
2.
Gao W, Kim M, Dykstra T, Du S, Boskovic P, Lichti C, et al.
Nature . 2024 Sep; 634(8034):693-701. PMID: 39232158
Traumatic injuries to the central nervous system (CNS) afflict millions of individuals worldwide, yet an effective treatment remains elusive. Following such injuries, the site is populated by a multitude of...
3.
Smyth L, Xu D, Okar S, Dykstra T, Rustenhoven J, Papadopoulos Z, et al.
Nature . 2024 Feb; 627(8002):165-173. PMID: 38326613
The arachnoid barrier delineates the border between the central nervous system and dura mater. Although the arachnoid barrier creates a partition, communication between the central nervous system and the dura...
4.
Xu W, Rustenhoven J, Nelson C, Dykstra T, Ferreiro A, Papadopoulos Z, et al.
Neuron . 2023 Aug; 111(20):3244-3254.e8. PMID: 37582366
Aging is a complex process involving various systems and behavioral changes. Altered immune regulation, dysbiosis, oxidative stress, and sleep decline are common features of aging, but their interconnection is poorly...
5.
Salvador A, Dykstra T, Rustenhoven J, Gao W, Blackburn S, Bhasiin K, et al.
Neuron . 2023 May; 111(14):2155-2169.e9. PMID: 37148871
Spinal cord injury (SCI) causes lifelong debilitating conditions. Previous works demonstrated the essential role of the immune system in recovery after SCI. Here, we explored the temporal changes of the...
6.
Brase L, You S, DOliveira Albanus R, Del-Aguila J, Dai Y, Novotny B, et al.
Nat Commun . 2023 Apr; 14(1):2314. PMID: 37085492
Genetic studies of Alzheimer disease (AD) have prioritized variants in genes related to the amyloid cascade, lipid metabolism, and neuroimmune modulation. However, the cell-specific effect of variants in these genes...
7.
Goldman D, Dykstra T, Smirnov I, Blackburn S, Da Mesquita S, Kipnis J, et al.
Nat Aging . 2023 Apr; 2(8):704-713. PMID: 37065770
Peripheral inflammation triggers a transient, well-defined set of behavioral changes known as sickness behavior, but the mechanisms by which inflammatory signals originating in the periphery alter activity in the brain...
8.
Rustenhoven J, Pavlou G, Storck S, Dykstra T, Du S, Wan Z, et al.
J Exp Med . 2023 Apr; 220(7). PMID: 37027179
The meningeal lymphatic network enables the drainage of cerebrospinal fluid (CSF) and facilitates the removal of central nervous system (CNS) waste. During aging and in Alzheimer's disease, impaired meningeal lymphatic...
9.
Drieu A, Du S, Storck S, Rustenhoven J, Papadopoulos Z, Dykstra T, et al.
Nature . 2022 Nov; 611(7936):585-593. PMID: 36352225
Macrophages are important players in the maintenance of tissue homeostasis. Perivascular and leptomeningeal macrophages reside near the central nervous system (CNS) parenchyma, and their role in CNS physiology has not...
10.
Sadick J, ODea M, Hasel P, Dykstra T, Faustin A, Liddelow S
Neuron . 2022 Apr; 110(11):1788-1805.e10. PMID: 35381189
Resolving glial contributions to Alzheimer's disease (AD) is necessary because changes in neuronal function, such as reduced synaptic density, altered electrophysiological properties, and degeneration, are not entirely cell autonomous. To...