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Justin Rustenhoven

Explore the profile of Justin Rustenhoven including associated specialties, affiliations and a list of published articles. Areas
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Articles 44
Citations 2032
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Recent Articles
1.
Gao W, Kim M, Dykstra T, Du S, Boskovic P, Lichti C, et al.
Nature . 2024 Sep; 634(8034):693-701. PMID: 39232158
Traumatic injuries to the central nervous system (CNS) afflict millions of individuals worldwide, yet an effective treatment remains elusive. Following such injuries, the site is populated by a multitude of...
2.
Du S, Drieu A, Cheng Y, Storck S, Rustenhoven J, Mamuladze T, et al.
bioRxiv . 2024 Aug; PMID: 39211090
Microglia are thought to originate exclusively from primitive macrophage progenitors in the yolk sac (YS) and to persist throughout life without much contribution from definitive hematopoiesis. Here, using lineage tracing,...
3.
Barclay K, Abduljawad N, Cheng Z, Kim M, Zhou L, Yang J, et al.
Immunity . 2024 May; 57(6):1394-1412.e8. PMID: 38821054
Recent single-cell RNA sequencing studies have revealed distinct microglial states in development and disease. These include proliferative-region-associated microglia (PAMs) in developing white matter and disease-associated microglia (DAMs) prevalent in various...
4.
Smyth L, Xu D, Okar S, Dykstra T, Rustenhoven J, Papadopoulos Z, et al.
Nature . 2024 Feb; 627(8002):165-173. PMID: 38326613
The arachnoid barrier delineates the border between the central nervous system and dura mater. Although the arachnoid barrier creates a partition, communication between the central nervous system and the dura...
5.
Barclay K, Abduljawad N, Cheng Z, Kim M, Zhou L, Yang J, et al.
bioRxiv . 2023 Dec; PMID: 38106187
Recent single-cell RNA sequencing studies have revealed distinct microglial states in development and disease. These include proliferative region-associated microglia (PAM) in developing white matter and disease-associated microglia (DAM) prevalent in...
6.
Mazzitelli J, Pulous F, Smyth L, Kaya Z, Rustenhoven J, Moskowitz M, et al.
Nat Neurosci . 2023 Nov; 26(12):2052-2062. PMID: 37996526
Decades of research have characterized diverse immune cells surveilling the CNS. More recently, the discovery of osseous channels (so-called 'skull channels') connecting the meninges with the skull and vertebral bone...
7.
Stevenson T, Hitpass Romero K, Rustenhoven J
Cell Stem Cell . 2023 Nov; 30(11):1395-1397. PMID: 37922875
Craniosynostosis is a congenital craniofacial disorder where premature fusion of cranial sutures causes elevated intracranial pressure and neurological deficits. In this issue of Cell Stem Cell, Ma et al. demonstrate...
8.
Stevenson T, Vinnell L, Rustenhoven J
Immunity . 2023 Oct; 56(10):2185-2187. PMID: 37820581
The increasing burden in dementia-related disorders has necessitated improved understanding of cognitive decline. In a recent issue of Nature, Schroer et al. demonstrate that platelet factor 4 in young blood...
9.
Xu W, Rustenhoven J, Nelson C, Dykstra T, Ferreiro A, Papadopoulos Z, et al.
Neuron . 2023 Aug; 111(20):3244-3254.e8. PMID: 37582366
Aging is a complex process involving various systems and behavioral changes. Altered immune regulation, dysbiosis, oxidative stress, and sleep decline are common features of aging, but their interconnection is poorly...
10.
Salvador A, Dykstra T, Rustenhoven J, Gao W, Blackburn S, Bhasiin K, et al.
Neuron . 2023 May; 111(14):2155-2169.e9. PMID: 37148871
Spinal cord injury (SCI) causes lifelong debilitating conditions. Previous works demonstrated the essential role of the immune system in recovery after SCI. Here, we explored the temporal changes of the...