Tahar van der Straaten
Overview
Explore the profile of Tahar van der Straaten including associated specialties, affiliations and a list of published articles.
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Articles
48
Citations
666
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0
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Recent Articles
21.
Ten Brink M, van Bavel T, Swen J, der Straaten T, Bredius R, Lankester A, et al.
Pharmacogenomics
. 2013 Nov;
14(14):1683-90.
PMID: 24192117
Background: Busulfan is used in preparative regimens prior to stem cell transplantation in pediatric patients. There is significant interpatient variability in busulfan pharmacokinetics (PK) and exposure is related to outcome....
22.
der Straaten T, Martijn R, el Hajoui T, Baak-Pablo R, Guchelaar H
Pharmacogenet Genomics
. 2013 Sep;
23(11):631-5.
PMID: 24061201
Monoclonal antibodies, such as rituximab, trastuzumab, and cetuximab, mediate immune response by binding to Fcγ receptors. The frequently occurring Phe158Val variant of the FCGR3A gene has increased binding affinity and...
23.
der Straaten T, Guchelaar H
Methods Mol Biol
. 2013 Jul;
1015:189-97.
PMID: 23824857
Since the human genome has been fully sequenced, and presence of single nucleotide polymorphisms (SNPs) appeared abundant, many studies are associating SNPs with clinical response or even with disease. For...
24.
Lu X, Liu Y, Yu T, Xiao S, Bao X, Pan L, et al.
PLoS One
. 2013 Apr;
8(4):e60006.
PMID: 23593158
Background: Benzo[a]pyrene(B[a]P), and its ultimate metabolite Benzo[a]pyrene 7,8-diol 9,10-epoxide (BPDE), are classic DNA damaging carcinogens. DNA damage caused by BPDE is normally repaired by Nucleotide Excision Repair (NER), of which...
25.
Yu T, Liu Y, Lu X, Xiao S, Cai Y, Jin C, et al.
Arch Toxicol
. 2012 Dec;
87(4):699-709.
PMID: 23203453
Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide (BPDE), a metabolite of Benzo[a]pyrene (B[a]P), is a high-risk factor for development of a number of cancers. DNA damage caused by BPDE is normally repaired by Nucleotide Excision Repair...
26.
Moes D, Press R, den Hartigh J, der Straaten T, De Fijter J, Guchelaar H
Clin Pharmacokinet
. 2012 May;
51(7):467-80.
PMID: 22624503
Background And Objective: Everolimus is a novel macrolide immunosuppressant used in the prevention of acute and chronic rejection of solid organ transplants. Everolimus is being actively investigated worldwide as a...
27.
der Straaten T, Guchelaar H, Swen J
Pharmacogenomics
. 2012 Mar;
13(4):369-72.
PMID: 22379992
No abstract available.
28.
Swen J, Baak-Pablo R, Guchelaar H, der Straaten T
Clin Chem Lab Med
. 2011 Oct;
50(2):279-84.
PMID: 22022982
Background: Several studies report difficulties in genotyping HNF1β rs757210 using TaqMan probes. This is possibly due to the tri-allelic nature of this single nucleotide polymorphism (SNP). The aim of the...
29.
Pander J, Heusinkveld M, der Straaten T, Jordanova E, Baak-Pablo R, Gelderblom H, et al.
Clin Cancer Res
. 2011 Jul;
17(17):5668-73.
PMID: 21788356
Purpose: In a recent randomized phase III clinical trial in metastatic colorectal cancer patients, the addition of the anti-epidermal growth factor receptor (EGFR) monoclonal antibody (mAb) cetuximab to bevacizumab and...
30.
Lu X, der Straaten T, Tiller M, Li X
J Clin Lab Anal
. 2011 May;
25(3):166-73.
PMID: 21567463
Analysis of gene expression can provide important information related to prognostic or predictive factors in clinical work. Analysis of DNA or RNA isolated from formalin fixed and paraffin-embedded tissue is...