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Tae Gyu Oh

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Articles 36
Citations 877
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Recent Articles
11.
Billon C, Sitaula S, Banerjee S, Welch R, Elgendy B, Hegazy L, et al.
ACS Chem Biol . 2023 Mar; 18(4):756-771. PMID: 36988910
Repetitive physical exercise induces physiological adaptations in skeletal muscle that improves exercise performance and is effective for the prevention and treatment of several diseases. Genetic evidence indicates that the orphan...
12.
Kang B, Park A, Yang H, Jo Y, Oh T, Jeong S, et al.
Sci Rep . 2022 Dec; 12(1):21842. PMID: 36528695
A simple predictive biomarker for fatty liver disease is required for individuals with insulin resistance. Here, we developed a supervised machine learning-based classifier for fatty liver disease using fecal 16S...
13.
Fu T, Li Y, Oh T, Cayabyab F, He N, Tang Q, et al.
Proc Natl Acad Sci U S A . 2022 Dec; 119(51):e2213041119. PMID: 36508655
The pleiotropic actions of the Farnesoid X Receptor (FXR) are required for gut health, and reciprocally, reduced intestinal FXR signaling is seen in inflammatory bowel diseases (IBDs). Here, we show...
14.
Sharpton S, Oh T, Madamba E, Wang C, Yu R, Atkins A, et al.
Aliment Pharmacol Ther . 2022 Sep; 56(10):1475-1485. PMID: 36164267
Background: There are limited data on the diagnostic accuracy of gut microbial signatures for predicting hepatic decompensation in patients with cirrhosis. Aims: To determine whether a stool metagenome-derived signature accurately...
15.
Kim J, Wang L, Sladky V, Oh T, Liu J, Trinh K, et al.
Cell Metab . 2022 Aug; 34(10):1548-1560.e6. PMID: 36041455
Sterol deficiency triggers SCAP-mediated SREBP activation, whereas hypernutrition together with ER stress activates SREBP1/2 via caspase-2. Whether these pathways interact and how they are selectively activated by different dietary cues...
16.
Yoon B, Oh T, Bu S, Seo K, Kwon S, Lee J, et al.
Mol Cells . 2022 Jul; 45(10):738-748. PMID: 35904026
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has posed a serious threat to global public health. A novel vaccine made from messenger RNA (mRNA) has been developed and...
17.
Choi J, Oh T, Jung H, Park K, Shin H, Jo T, et al.
Gastroenterology . 2022 Apr; 163(1):239-256. PMID: 35461826
Background & Aims: Mitochondrial dysfunction disrupts the synthesis and secretion of digestive enzymes in pancreatic acinar cells and plays a primary role in the etiology of exocrine pancreas disorders. However,...
18.
Yang L, TeSlaa T, Ng S, Nofal M, Wang L, Lan T, et al.
Med . 2022 Apr; 3(2):119-136. PMID: 35425930
Background: Ketogenic diet is a potential means of augmenting cancer therapy. Here, we explore ketone body metabolism and its interplay with chemotherapy in pancreatic cancer. Methods: Metabolism and therapeutic responses...
19.
Wang L, Oh T, Magida J, Estepa G, Obayomi S, Chong L, et al.
Proc Natl Acad Sci U S A . 2021 Aug; 118(35). PMID: 34446564
In macrophages, homeostatic and immune signals induce distinct sets of transcriptional responses, defining cellular identity and functional states. The activity of lineage-specific and signal-induced transcription factors are regulated by chromatin...
20.
Oh T, Jo J, Lee S
J Food Sci . 2021 Jun; 86(7):2872-2885. PMID: 34146411
Enzyme-based time-temperature integrators (TTIs) were applied to indicate the ripeness of plastic-container-packaged kiwifruit. The hypothesis was that the ethylene gas production, an indication of kiwifruit ripeness, depends on the time-temperature...