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Annette R Atkins

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Articles 54
Citations 5333
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Recent Articles
1.
Wang H, Fan W, Liu S, Kim K, Matsushima A, Ogawa S, et al.
Proc Natl Acad Sci U S A . 2025 Jan; 122(4):e2408896122. PMID: 39841144
Nutritional status is a determining factor for growth during development and homeostatic maintenance in adulthood. In the context of muscle, growth hormone (GH) coordinates growth with nutritional status; however, the...
2.
Pessentheiner A, Spann N, Autran C, Oh T, Grunddal K, Coker J, et al.
JCI Insight . 2024 Sep; 9(21). PMID: 39325548
Macrophages contribute to the induction and resolution of inflammation and play a central role in chronic low-grade inflammation in cardiovascular diseases caused by atherosclerosis. Human milk oligosaccharides (HMOs) are complex...
3.
Hong S, Castro G, Wang D, Nofsinger R, Kane M, Folias A, et al.
Proc Natl Acad Sci U S A . 2024 Feb; 121(9):e2320129121. PMID: 38377195
Despite numerous female contraceptive options, nearly half of all pregnancies are unintended. Family planning choices for men are currently limited to unreliable condoms and invasive vasectomies with questionable reversibility. Here,...
4.
Liang G, Oh T, Hah N, Tiriac H, Shi Y, Truitt M, et al.
Nat Commun . 2023 Dec; 14(1):7791. PMID: 38057326
Oncogenic lesions in pancreatic ductal adenocarcinoma (PDAC) hijack the epigenetic machinery in stromal components to establish a desmoplastic and therapeutic resistant tumor microenvironment (TME). Here we identify Class I histone...
5.
Liang G, Oh T, Hah N, Tiriac H, Shi Y, Truitt M, et al.
bioRxiv . 2023 Sep; PMID: 37745372
Oncogenic lesions in pancreatic ductal adenocarcinoma (PDAC) hijack the epigenetic machinery in stromal components to establish a desmoplastic and therapeutic resistant tumor microenvironment (TME). Here we identify Class I histone...
6.
Antal C, Oh T, Aigner S, Luo E, Yee B, Campos T, et al.
Nat Commun . 2023 Sep; 14(1):5195. PMID: 37673892
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy in need of new therapeutic options. Using unbiased analyses of super-enhancers (SEs) as sentinels of core genes involved in cell-specific function, here...
7.
Yoon B, Kim H, Oh T, Oh S, Jo S, Kim M, et al.
Proc Natl Acad Sci U S A . 2023 May; 120(21):e2217826120. PMID: 37192160
Molecular classification of gastric cancer (GC) identified a subgroup of patients showing chemoresistance and poor prognosis, termed SEM (Stem-like/Epithelial-to-mesenchymal transition/Mesenchymal) type in this study. Here, we show that SEM-type GC...
8.
Sharpton S, Oh T, Madamba E, Wang C, Yu R, Atkins A, et al.
Aliment Pharmacol Ther . 2022 Sep; 56(10):1475-1485. PMID: 36164267
Background: There are limited data on the diagnostic accuracy of gut microbial signatures for predicting hepatic decompensation in patients with cirrhosis. Aims: To determine whether a stool metagenome-derived signature accurately...
9.
Choi J, Oh T, Jung H, Park K, Shin H, Jo T, et al.
Gastroenterology . 2022 Apr; 163(1):239-256. PMID: 35461826
Background & Aims: Mitochondrial dysfunction disrupts the synthesis and secretion of digestive enzymes in pancreatic acinar cells and plays a primary role in the etiology of exocrine pancreas disorders. However,...
10.
Bapat S, Whitty C, Mowery C, Liang Y, Yoo A, Jiang Z, et al.
Nature . 2022 Mar; 604(7905):337-342. PMID: 35355021
Decades of work have elucidated cytokine signalling and transcriptional pathways that control T cell differentiation and have led the way to targeted biologic therapies that are effective in a range...