Tae-Hoon Lee
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Explore the profile of Tae-Hoon Lee including associated specialties, affiliations and a list of published articles.
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163
Citations
1665
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Recent Articles
1.
Ahn H, Byun B, Lee T, Kang D, Park S
PLoS One
. 2024 Nov;
19(11):e0314204.
PMID: 39576809
Background: The use of medicines is crucial in treatment, but nonadherence poses an important challenge, particularly when managing polypharmacy and long-term conditions. Pharmacist-led home visit services offer a promising solution...
2.
Encarnacion A, Pootheri N, Yao H, Chen Z, Lee S, Kim E, et al.
Bioorg Med Chem Lett
. 2024 Jul;
110:129884.
PMID: 38996939
Both cyclopropyl amide and piperazine sulfonamide functional groups are known for their various biological properties used for drug development. Herein, we synthesized nine new derivatives with different substituent groups incorporating...
3.
Chen Z, Choi E, Encarnacion A, Yao H, Ding M, Park Y, et al.
Bioorg Chem
. 2024 Jul;
150:107603.
PMID: 38968905
Inhibition of LSD1 was proposed as promising and attractive therapies for treating osteoporosis. Here, we synthesized a series of novel TCP-(MP)-Caffeic acid analogs as potential LSD1 inhibitors to assess their...
4.
Chen Z, Encarnacion A, Rajan R, Yao H, Lee S, Kim E, et al.
Eur J Med Chem
. 2024 Mar;
270:116335.
PMID: 38555854
Several flavonoids have been shown to exert anti-osteoporosis activity. However, the structure-activity relationship and the mechanism of anti-osteoporosis activity of flavonoids remain unknown. In this study, we prepared a series...
5.
Suk S, Lee T
Facial Plast Surg Aesthet Med
. 2024 Mar;
26(5):587-592.
PMID: 38466953
Although anterior septal reconstruction (ASR) is effective, it is less commonly employed in Asian patients compared with the septal extension graft technique, even in cases of severe antero-caudal septal deviation....
6.
Chen Z, Joseph D, Ding M, Bhujbal S, Rajan R, Kim E, et al.
Eur J Med Chem
. 2023 Aug;
260:115767.
PMID: 37651877
Abnormal osteoclast differentiation causes various bone disorders such as osteoporosis. Targeting the formation and activation of osteoclasts has been recognized as an effective approach for preventing osteoporosis. Herein, we synthesized...
7.
Jeong J, Lee D, Park B, Lee T, Park S
Stem Cell Res
. 2023 Jul;
71:103167.
PMID: 37481965
A TNFRSF11B (TNF Receptor Superfamily Member 11b) gene encodes a soluble decoy receptor, osteoprotegerin (OPG), which has a key role in repressing osteoclast differentiation. In this report, we generated a...
8.
Lee T, Kim J, Baek S, Kwak J, Kim J
J Gastrointest Surg
. 2023 Jul;
27(8):1694-1701.
PMID: 37407895
Background: Serum carcinoembryonic antigen (CEA) increase in patients with colorectal cancer (CRC) recurrence was observed to vary depending on their initial values. This study aimed to evaluate the diagnostic accuracy...
9.
Hwang-Bo J, Veerappan K, Moon H, Lee T, Lee K, Park J, et al.
Biomedicines
. 2023 May;
11(5).
PMID: 37239060
Atopic dermatitis (AD) is a chronic inflammatory skin disease which requires continuous treatment due to its relapsing nature. The current treatment includes steroids and nonsteroidal agents targeting inflammation but long-term...
10.
Chen Z, Rajamanickam K, Ding M, Kim S, Park S, Kim E, et al.
J Med Chem
. 2023 May;
66(10):6766-6781.
PMID: 37151031
To discover a potent candidate for suppressing mature osteoclasts formation using a TRAP staining assay. A series of PMSA derivatives were synthesized and evaluated for their bioactivity in our current...