T W Harrity
Overview
Explore the profile of T W Harrity including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
149
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Robl J, Sulsky R, Sun C, Simpkins L, Wang T, Dickson Jr J, et al.
J Med Chem
. 2001 Apr;
44(6):851-6.
PMID: 11300866
A series of benzimidazole-based analogues of the potent MTP inhibitor BMS-201038 were discovered. Incorporation of an unsubstituted benzimidazole moiety in place of a piperidine group afforded potent inhibitors of MTP...
2.
Wetterau J, GREGG R, Harrity T, Arbeeny C, Cap M, Connolly F, et al.
Science
. 1998 Oct;
282(5389):751-4.
PMID: 9784135
Patients with abetalipoproteinemia, a disease caused by defects in the microsomal triglyceride transfer protein (MTP), do not produce apolipoprotein B-containing lipoproteins. It was hypothesized that small molecule inhibitors of MTP...
3.
Jamil H, Gordon D, Eustice D, Brooks C, Dickson Jr J, Chen Y, et al.
Proc Natl Acad Sci U S A
. 1996 Oct;
93(21):11991-5.
PMID: 8876250
The microsomal triglyceride (TG) transfer protein (MTP) is a heterodimeric lipid transfer protein that catalyzes the transport of triglyceride, cholesteryl ester, and phosphatidylcholine between membranes. Previous studies showing that the...
4.
Dickson Jr J, Biller S, Magnin D, Petrillo Jr E, Hillyer J, Hsieh D, et al.
J Med Chem
. 1996 Feb;
39(3):661-4.
PMID: 8576906
No abstract available.
5.
Magnin D, Biller S, Chen Y, Dickson Jr J, Fryszman O, Lawrence R, et al.
J Med Chem
. 1996 Feb;
39(3):657-60.
PMID: 8576905
No abstract available.
6.
Magnin D, Biller S, Dickson Jr J, Logan J, Lawrence R, Chen Y, et al.
J Med Chem
. 1995 Jul;
38(14):2596-605.
PMID: 7629799
Inhibitors of squalene synthase have the potential to be superior cholesterol-lowering agents. We previously disclosed that lipophilic 1,1-bisphosphonates I are potent squalene synthase inhibitors and orally active cholesterol-lowering agents in...
7.
Ciosek Jr C, Magnin D, Harrity T, Logan J, Dickson Jr J, Gordon E, et al.
J Biol Chem
. 1993 Nov;
268(33):24832-7.
PMID: 8227045
Squalene synthase catalyzes the reductive dimerization of two molecules of farnesyl diphosphate to form squalene at the final branchpoint of the cholesterol biosynthetic pathway. We report herein that isoprenyl 1,1-bisphosphonates...
8.
Robl J, Duncan L, Pluscec J, Karanewsky D, Gordon E, Ciosek Jr C, et al.
J Med Chem
. 1991 Sep;
34(9):2804-15.
PMID: 1895299
A series of 2,3,4,(5),6-substituted pyridines containing a hydroxyphosphinyl functionally have been prepared and were evaluated for their ability to inhibit the enzyme HMG-CoA reductase. Systematic substitution of both R1-R4 and...
9.
Karanewsky D, Badia M, Ciosek Jr C, Robl J, Sofia M, Simpkins L, et al.
J Med Chem
. 1990 Nov;
33(11):2952-6.
PMID: 2231594
No abstract available.
10.
Ciosek Jr C, Harrity T
J Lab Clin Med
. 1980 Sep;
96(3):460-9.
PMID: 6249878
Rabbit articular cartilage fragments from knees with normal and antigen-induced chronic synovitis were assayed for active and latent collagenolytic activity. Significant levels of latent collagenolytic activity, as measured by hydroxyproline...