T T Kung
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Explore the profile of T T Kung including associated specialties, affiliations and a list of published articles.
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25
Citations
352
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Recent Articles
1.
Kung T, Crawley Y, Jones H, Luo B, Gilchrest H, Greenfeder S, et al.
Pharmacol Res
. 2004 Oct;
50(6):611-5.
PMID: 15501700
Tachykinins are important in the development of pulmonary inflammation in mice but the tachykinin receptor subtype mediating this response has not been defined. To elucidate the role of tachykinin NK3-receptors...
2.
Kung T, Luo B, Crawley Y, Garlisi C, Devito K, Minnicozzi M, et al.
Am J Respir Cell Mol Biol
. 2001 Nov;
25(5):600-5.
PMID: 11713102
Interleukin (IL)-9 is a T-cell-derived cytokine with pleiotropic activities on T helper 2 cells, B cells, and mast cells. IL-9 may therefore play an important role in the development of...
3.
Spond J, Chapman R, Fine J, Jones H, Kreutner W, Kung T, et al.
Pulm Pharmacol Ther
. 2001 Mar;
14(2):157-64.
PMID: 11273798
Using a rat model of lipopolysaccharide (LPS)-induced pulmonary inflammation, the antiinflammatory activity of SB 207499 was evaluated and compared to that of the prototypic type-4 phosphodiesterase (PDE4) inhibitor, rolipram. In...
4.
Kung T, Crawley Y, Luo B, Young S, Kreutner W, Chapman R
Br J Pharmacol
. 2000 May;
130(2):457-63.
PMID: 10807686
This study investigates the role of adrenal-derived catecholamines and corticosterone on the inhibition by rolipram, a phosphodiesterase (PDE)-4 inhibitor, of pulmonary eosinophilia and airway hyperresponsiveness (AHR) in allergic mice. The...
5.
Egan R, Athwal D, Bodmer M, Carter J, Chapman R, Chou C, et al.
Arzneimittelforschung
. 1999 Oct;
49(9):779-90.
PMID: 10514907
This report describes the development and the biology of Sch 55700, a humanized monoclonal antibody to human IL-5 (hIL-5). Sch 55700 was synthesized using CDR (complementarity determining regions) grafting technology...
6.
Umland S, Shah H, Jakway J, Shortall J, Razac S, Garlisi C, et al.
Am J Respir Cell Mol Biol
. 1999 Feb;
20(3):481-92.
PMID: 10030847
We compared the effects of cyclosporin A (CSA) and a macrotetrolide antibiotic, dinactin, on human T-cell proliferation and cytokine production induced by stimulation of the T-cell receptor alone (monoclonal antibody...
7.
Garlisi C, Kung T, Wang P, Minnicozzi M, Umland S, Chapman R, et al.
Am J Respir Cell Mol Biol
. 1999 Jan;
20(2):248-55.
PMID: 9922215
The maturation of eosinophils in bone marrow, their migration to pulmonary tissue, and their subsequent degranulation and release of toxic granule proteins contributes to the pathophysiology observed in asthma. Interleukin-5...
8.
Chapman R, Sehring S, Garlisi C, Falcone A, Kung T, Stelts D, et al.
Arzneimittelforschung
. 1998 Jun;
48(4):384-91.
PMID: 9608881
Mometasone furoate (CAS 83919-23-7, Sch 32088) is a new inhaled corticosteroid that is being developed to treat allergic inflammatory airway disorders such as rhinitis and asthma. In this study, we...
9.
Stelts D, Egan R, Falcone A, Garlisi C, Gleich G, Kreutner W, et al.
Am J Respir Cell Mol Biol
. 1998 May;
18(4):463-70.
PMID: 9533933
Accumulation of eosinophils in the lung with concomitant tissue damage are defining histopathologic features of human asthma. Through degranulation and the release of proinflammatory proteins such as major basic protein...
10.