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D Stelts

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Recent Articles
1.
Egan R, Athwal D, Bodmer M, Carter J, Chapman R, Chou C, et al.
Arzneimittelforschung . 1999 Oct; 49(9):779-90. PMID: 10514907
This report describes the development and the biology of Sch 55700, a humanized monoclonal antibody to human IL-5 (hIL-5). Sch 55700 was synthesized using CDR (complementarity determining regions) grafting technology...
2.
Umland S, Shah H, Jakway J, Shortall J, Razac S, Garlisi C, et al.
Am J Respir Cell Mol Biol . 1999 Feb; 20(3):481-92. PMID: 10030847
We compared the effects of cyclosporin A (CSA) and a macrotetrolide antibiotic, dinactin, on human T-cell proliferation and cytokine production induced by stimulation of the T-cell receptor alone (monoclonal antibody...
3.
Garlisi C, Kung T, Wang P, Minnicozzi M, Umland S, Chapman R, et al.
Am J Respir Cell Mol Biol . 1999 Jan; 20(2):248-55. PMID: 9922215
The maturation of eosinophils in bone marrow, their migration to pulmonary tissue, and their subsequent degranulation and release of toxic granule proteins contributes to the pathophysiology observed in asthma. Interleukin-5...
4.
Chapman R, Sehring S, Garlisi C, Falcone A, Kung T, Stelts D, et al.
Arzneimittelforschung . 1998 Jun; 48(4):384-91. PMID: 9608881
Mometasone furoate (CAS 83919-23-7, Sch 32088) is a new inhaled corticosteroid that is being developed to treat allergic inflammatory airway disorders such as rhinitis and asthma. In this study, we...
5.
Stelts D, Egan R, Falcone A, Garlisi C, Gleich G, Kreutner W, et al.
Am J Respir Cell Mol Biol . 1998 May; 18(4):463-70. PMID: 9533933
Accumulation of eosinophils in the lung with concomitant tissue damage are defining histopathologic features of human asthma. Through degranulation and the release of proinflammatory proteins such as major basic protein...
6.
Feder L, Stelts D, Chapman R, Manfra D, Crawley Y, Jones H, et al.
Am J Respir Cell Mol Biol . 1997 Nov; 17(4):436-42. PMID: 9376118
Nitric oxide (NO) is an important mediator of inflammatory reactions and may contribute to the lung inflammation in allergic pulmonary diseases. To assess the role of NO in pulmonary inflammation,...
7.
Vining D, Zagoria R, Liu K, Stelts D
AJR Am J Roentgenol . 1996 Feb; 166(2):409-10. PMID: 8553956
No abstract available.
8.
Kung T, Stelts D, Zurcher J, Jones H, Umland S, Kreutner W, et al.
Am J Respir Cell Mol Biol . 1995 Apr; 12(4):404-9. PMID: 7695919
Mast cells are important effector cells in IgE-mediated acute allergic reactions. Mast cells also produce cytokines such as interleukin (IL)-3, IL-4, IL-5, tumor necrosis factor (TNF), and granulocyte-macrophage colony-stimulating factor...
9.
Garlisi C, Falcone A, Kung T, Stelts D, Pennline K, Beavis A, et al.
Clin Immunol Immunopathol . 1995 Apr; 75(1):75-83. PMID: 7533686
In a murine model of pulmonary inflammation, aerosolized antigen challenge of sensitized B6D2F1 mice leads to eosinophil accumulation within the lungs. Little is known of the role of T cells...
10.
Kung T, Stelts D, Zurcher J, WATNICK A, Jones H, Mauser P, et al.
J Allergy Clin Immunol . 1994 Dec; 94(6 Pt 2):1217-24. PMID: 7798563
No abstract available.