T R Kannan
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Explore the profile of T R Kannan including associated specialties, affiliations and a list of published articles.
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34
Citations
914
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Recent Articles
1.
Ramasamy K, Balasubramanian S, Kirkpatrick A, Szabo D, Pandranki L, Baseman J, et al.
Sci Rep
. 2021 Jun;
11(1):11571.
PMID: 34078958
Mycoplasma pneumoniae is the leading cause of bacterial community-acquired pneumonia among hospitalized children in the United States. It is also responsible for a spectrum of other respiratory tract disorders and ...
2.
Ramasamy K, Balasubramanian S, Manickam K, Pandranki L, Taylor A, Hart P, et al.
mBio
. 2018 Jan;
9(1).
PMID: 29362229
is an atypical bacterium that causes respiratory illnesses in humans, including pharyngitis, tracheobronchitis, and community-acquired pneumonia (CAP). It has also been directly linked to reactive airway disease, asthma, and extrapulmonary...
3.
Tsai S, Segovia J, Chang T, Shil N, Pokharel S, Kannan T, et al.
J Immunol
. 2015 Sep;
195(9):4426-37.
PMID: 26385519
Recognition of viral dsRNA by endosomal TLR3 activates innate immune response during virus infection. Trafficking of TLR3 to the endolysosomal compartment arising from fusion of late endosome (LE) with lysosome...
4.
Becker A, Kannan T, Taylor A, Pakhomova O, Zhang Y, Somarajan S, et al.
Proc Natl Acad Sci U S A
. 2015 Apr;
112(16):5165-70.
PMID: 25848012
Mycoplasma pneumoniae (Mp) infections cause tracheobronchitis and "walking" pneumonia, and are linked to asthma and other reactive airway diseases. As part of the infectious process, the bacterium expresses a 591-aa...
5.
Bose S, Segovia J, Somarajan S, Chang T, Kannan T, Baseman J
mBio
. 2014 Dec;
5(6).
PMID: 25538194
Unlabelled: The inflammasome is a major regulator of inflammation through its activation of procaspase-1, which cleaves prointerleukin-1β (pro-IL-1β) into its mature form. IL-1β is a critical proinflammatory cytokine that dictates...
6.
Somarajan S, Al-Asadi F, Ramasamy K, Pandranki L, Baseman J, Kannan T
mBio
. 2014 Aug;
5(4).
PMID: 25139904
Unlabelled: Mycoplasma pneumoniae synthesizes a novel human surfactant protein A (SP-A)-binding cytotoxin, designated community-acquired respiratory distress syndrome (CARDS) toxin, that exhibits ADP-ribosylating and vacuolating activities in mammalian cells and is...
7.
Medina J, Coalson J, Brooks E, Jourdan Le Saux C, Winter V, Chaparro A, et al.
PLoS One
. 2014 Jul;
9(7):e102613.
PMID: 25058417
Mycoplasma pneumoniae causes a range of airway and extrapulmonary pathologies in humans. Clinically, M. pneumoniae is associated with acute exacerbations of human asthma and a worsening of experimentally induced asthma...
8.
Sachdeva R, Kannan T, Mendonca C, Patteril M
Anaesthesia
. 2014 May;
69(8):826-31.
PMID: 24807288
The practice of checking the ability to mask ventilate before administering neuromuscular blocking drugs remains controversial. We prospectively evaluated the changes in the expired tidal volume during pressure-controlled ventilation (two-handed...
9.
Krishnan M, Kannan T, Baseman J
PLoS One
. 2013 May;
8(5):e62706.
PMID: 23667510
Bacterial toxins possess specific mechanisms of binding and uptake by mammalian cells. Mycoplasma pneumoniae CARDS (Community Acquired Respiratory Distress Syndrome) toxin is a 68 kDa protein, which demonstrates high binding...
10.
Musatovova O, Kannan T, Baseman J
PLoS One
. 2012 Oct;
7(10):e47625.
PMID: 23091634
Mycoplasma pneumoniae is the smallest self-replicating bacterium with a streamlined genome of 0.81 Mb. Complete genome analysis revealed the presence of multiple copies of four large repetitive elements (designated RepMP1,...