T R Devereux
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Explore the profile of T R Devereux including associated specialties, affiliations and a list of published articles.
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80
Citations
855
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Recent Articles
1.
Sills R, Hong H, Flake G, Moomaw C, Clayton N, Boorman G, et al.
Carcinogenesis
. 2003 Dec;
25(4):605-12.
PMID: 14688030
In the previous 500 2-year chemical bioassays within the National Toxicology Program, large intestinal tumors (cecal carcinomas) related to chemical exposure have not been observed in B6C3F1 mice. The recently...
2.
Hong H, Ton T, Devereux T, Moomaw C, Clayton N, Chan P, et al.
Toxicol Appl Pharmacol
. 2003 Sep;
191(3):227-34.
PMID: 13678655
The most prominent neoplastic lesions in mice in the 2-year studies of o-nitrotoluene and riddelliine were hemangiosarcomas. Fifteen o-nitrotoluene-induced hemangiosarcomas of the skeletal muscle, subcutaneous tissue, and mesentery; 12 riddelliine-induced...
3.
Mingchao , Devereux T, Stockton P, Sun K, Sills R, Clayton N, et al.
Exp Toxicol Pathol
. 2001 Oct;
53(4):237-46.
PMID: 11665847
Gastric cancers are commonly subdivided into intestinal and diffuse subtypes on a morphologic basis, supported by corollary evidence of differences at the pathogenetic and molecular levels. Chronic atrophic gastritis with...
4.
Hayashi S, HONG H, Toyoda K, Ton T, Devereux T, Maronpot R, et al.
Toxicol Pathol
. 2001 Sep;
29(4):422-9.
PMID: 11560247
1-Amino-2,4-dibromoanthraquinone (ADBAQ) is an anthraquinone-derived vat dye, and a potent carcinogen in laboratory animals. In a 2-year study with dietary exposure to 10,000 or 20,000 ppm ADBAQ, increased incidence of...
5.
Zhang Z, Wang Y, Vikis H, Johnson L, Liu G, Li J, et al.
Nat Genet
. 2001 Aug;
29(1):25-33.
PMID: 11528387
Although the ras genes have long been established as proto-oncogenes, the dominant role of activated ras in cell transformation has been questioned. Previous studies have shown frequent loss of the...
6.
Devereux T, Stern M, Flake G, Yu M, Zhang Z, London S, et al.
Mol Carcinog
. 2001 Jun;
31(2):68-73.
PMID: 11429783
beta-Catenin plays a key role in the Wnt signaling pathway, and mutations of CTNNB1, the gene that encodes beta-catenin, have been identified in about one-fourth of human hepatocellular carcinomas from...
7.
Sills R, Hong H, Boorman G, Devereux T, Melnick R
Chem Biol Interact
. 2001 Jun;
135-136:373-86.
PMID: 11397402
1,3 Butadiene (BD), isoprene (IP) and chloroprene (CP) are structural analogs. There were significantly increased incidences of forestomach neoplasms in B6C3F1 mice exposed to BD, IP or CP by inhalation...
8.
Zhang Z, Lin L, Liu G, Wang M, Hill J, Wang Y, et al.
Exp Lung Res
. 2001 Feb;
26(8):627-39.
PMID: 11195460
In a number of recent studies, a lung tumor resistance locus designated either Par2 or Pas7 was mapped to distal chromosome 18 in crosses between susceptible A/J and more resistant...
9.
Patel A, Anna C, Foley J, Stockton P, Tyson F, Barrett J, et al.
Carcinogenesis
. 2000 Aug;
21(9):1691-700.
PMID: 10964101
Primary lung tumors from B6C3F1 mice and mouse lung cell lines were examined to investigate the role of transcriptional silencing of the p16 (Ink4a) tumor suppressor gene by DNA hypermethylation...
10.
HONG H, Devereux T, Melnick R, Moomaw C, Boorman G, Sills R
Toxicol Pathol
. 2000 Aug;
28(4):529-34.
PMID: 10930038
1,3-Butadiene is a multisite carcinogen in rodents. Incidences of cardiac hemangiosarcomas were significantly increased in male and female B6C3F1 mice that inhaled 1,3-butadiene (BD) for 2 years. Eleven BD-induced cardiac...