T R Cummins
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Explore the profile of T R Cummins including associated specialties, affiliations and a list of published articles.
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49
Citations
2489
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Recent Articles
11.
Cummins T, Aglieco F, Renganathan M, Herzog R, Dib-Hajj S, Waxman S
J Neurosci
. 2001 Aug;
21(16):5952-61.
PMID: 11487618
Although rat brain Nav1.3 voltage-gated sodium channels have been expressed and studied in Xenopus oocytes, these channels have not been studied after their expression in mammalian cells. We characterized the...
12.
Waxman S, Cummins T, Dib-Hajj S, Black J
J Rehabil Res Dev
. 2001 Apr;
37(5):517-28.
PMID: 11322150
Pain pathways begin with spinal sensory (dorsal root ganglion, DRG) neurons that produce nociceptive signals and convey them centrally. Following injury to the nervous system, DRG neurons can become hyperexcitable,...
13.
Kearney J, Plummer N, Smith M, Kapur J, Cummins T, Waxman S, et al.
Neuroscience
. 2001 Feb;
102(2):307-17.
PMID: 11166117
The GAL879-881QQQ mutation in the cytoplasmic S4-S5 linker of domain 2 of the rat brain IIA sodium channel (Na(v)1.2) results in slowed inactivation and increased persistent current when expressed in...
14.
Waxman S, Dib-Hajj S, Cummins T, Black J
Brain Res
. 2000 Dec;
886(1-2):5-14.
PMID: 11119683
Although classical neurophysiological doctrine rested on the concept of the sodium channel, it is now clear that there are nearly a dozen sodium channel genes, each encoding a molecularly distinct...
15.
Cummins T, Dib-Hajj S, Black J, Waxman S
Prog Brain Res
. 2000 Dec;
129:3-19.
PMID: 11098678
No abstract available.
16.
Sleeper A, Cummins T, Dib-Hajj S, Hormuzdiar W, Tyrrell L, Waxman S, et al.
J Neurosci
. 2000 Sep;
20(19):7279-89.
PMID: 11007885
Two TTX-resistant sodium channels, SNS and NaN, are preferentially expressed in c-type dorsal root ganglion (DRG) neurons and have been shown recently to have distinct electrophysiological signatures, SNS producing a...
17.
Renganathan M, Cummins T, Hormuzdiar W, Waxman S
J Neurophysiol
. 2000 Aug;
84(2):710-8.
PMID: 10938298
In this study, we used sensory neuron specific (SNS) sodium channel gene knockout (-/-) mice to ask whether SNS sodium channel produces the slow Na(+) current ("slow") in large (>40...
18.
Bendahhou S, Cummins T, Hahn A, Langlois S, Waxman S, Ptacek L
J Clin Invest
. 2000 Aug;
106(3):431-8.
PMID: 10930446
Hyperkalemic periodic paralysis (HyperKPP) is an autosomal dominant skeletal muscle disorder caused by single mutations in the SCN4A gene, encoding the human skeletal muscle voltage-gated Na(+) channel. We have now...
19.
Renganathan M, Cummins T, Hormuzdiar W, Black J, Waxman S
J Neurophysiol
. 2000 Apr;
83(4):2431-42.
PMID: 10758144
In this study, we examined whether nitric oxide synthase (NOS) is upregulated in small dorsal root ganglion (DRG) neurons after axotomy and, if so, whether the upregulation of NOS modulates...
20.
Cummins T, Black J, Dib-Hajj S, Waxman S
J Neurosci
. 2000 Jan;
20(23):8754-61.
PMID: 11102483
Dorsal root ganglion (DRG) neurons produce multiple sodium currents, including several different TTX-sensitive (TTX-S) currents and TTX-resistant (TTX-R) currents, which are produced by distinct sodium channels. We previously demonstrated that,...