T P Keith
Overview
Explore the profile of T P Keith including associated specialties, affiliations and a list of published articles.
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19
Citations
527
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Recent Articles
1.
Iwanaga T, McEuen A, Walls A, Clough J, Keith T, Rorke S, et al.
Clin Exp Allergy
. 2004 Jul;
34(7):1037-42.
PMID: 15248847
Background: Mast cell chymase has the potential to be an important mediator of inflammation and remodelling in the asthmatic lung. Previous studies have examined association between promoter polymorphism of the...
2.
Yang I, Barton S, Rorke S, Cakebread J, Keith T, Clough J, et al.
Genes Immun
. 2004 Jan;
5(1):41-5.
PMID: 14735148
Endotoxin exposure may have a protective effect against asthma and atopy. An Asp299Gly polymorphism in the Toll-like receptor 4 (TLR4) gene reduces responsiveness to endotoxin. This study determined the effect...
3.
Beghe B, Barton S, Rorke S, Peng Q, Sayers I, Gaunt T, et al.
Clin Exp Allergy
. 2003 Aug;
33(8):1111-7.
PMID: 12911786
Background: IL-4 by binding to its receptor (IL-4R) is essential for the development of airway inflammation present in asthma, through the induction of IgE synthesis in B cells and differentiation...
4.
In K, Silverman E, Asano K, Beier D, Fischer A, Keith T, et al.
Clin Rev Allergy Immunol
. 1999 Aug;
17(1-2):59-69.
PMID: 10436859
Our data demonstrate the presence of a naturally occurring family of alleles in the core promoter of the 5-LO gene, which is characterized by the deletion or addition of consensus...
5.
Ginns E, St Jean P, Philibert R, Galdzicka M, Thiel B, Long R, et al.
Proc Natl Acad Sci U S A
. 1998 Dec;
95(26):15531-6.
PMID: 9861003
Bipolar affective disorder (BPAD; manic-depressive illness) is characterized by episodes of mania and/or hypomania interspersed with periods of depression. Compelling evidence supports a significant genetic component in the susceptibility to...
6.
In K, Asano K, Beier D, Grobholz J, Finn P, Silverman E, et al.
J Clin Invest
. 1997 Mar;
99(5):1130-7.
PMID: 9062372
Five lipoxygenase (5-LO) is the first committed enzyme in the metabolic pathway leading to the synthesis of the leukotrienes. We examined genomic DNA isolated from 25 normal subjects and 31...
7.
Ginns E, Ott J, Egeland J, Allen C, Fann C, Pauls D, et al.
Nat Genet
. 1996 Apr;
12(4):431-5.
PMID: 8630500
The most characteristic features of bipolar affective disorder (manic-depressive illness) are episodes of mania (bipolar I, BPI) or hypomania (bipolar II, BPII) interspersed with periods of depression. Manic-depressive illness afflicts...
8.
Pauls D, Ott J, Paul S, Allen C, Fann C, Carulli J, et al.
Am J Hum Genet
. 1995 Sep;
57(3):636-43.
PMID: 7668292
Previously reported linkage of bipolar affective disorder to DNA markers in the pericentromeric region of chromosome 18 was reexamined in a larger homogeneous sample of Old Order Amish families. Four...
9.
Kozman H, Keith T, Donis-Keller H, White R, Weissenbach J, Dean M, et al.
Genomics
. 1995 Jan;
25(1):44-58.
PMID: 7774955
A Centre d'Etude du Polymorphisme Humain (CEPH) consortium map of human chromosome 16 has been constructed. The map contains 158 loci defined by 191 different probe/restriction enzyme combinations or primer...
10.
Ting C, Burgess D, Chamberlain J, Keith T, Falls K, Meisler M
Genomics
. 1993 Jun;
16(3):698-706.
PMID: 8325643
The human PCK1 gene encoding phosphoenolpyruvate carboxykinase (GTP) (PEPCK) was isolated and sequenced. There is 91% amino acid sequence identity (567/622 residues) between the human and the rat proteins, with...