T Neil Dear
Overview
Explore the profile of T Neil Dear including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
1434
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0
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Recent Articles
1.
Johnston J, Angyal A, Bauer R, Hamby S, Suvarna S, Baidzajevas K, et al.
Sci Adv
. 2019 Nov;
5(10):eaax9183.
PMID: 31692955
Macrophages drive atherosclerotic plaque progression and rupture; hence, attenuating their atherosclerosis-inducing properties holds promise for reducing coronary heart disease (CHD). Recent studies in mouse models have demonstrated that Tribbles 1...
2.
Diggle C, Martinez-Garay I, Molnar Z, Brinkworth M, White E, Fowler E, et al.
PLoS One
. 2017 Apr;
12(4):e0174264.
PMID: 28388629
Tubulin alpha 8 (Tuba8) is the most divergent member of the highly conserved alpha tubulin family, and uniquely lacks two key post-translational modification sites. It is abundantly expressed in testis...
3.
Cahill T, Leo V, Kelly M, Stockenhuber A, Kennedy N, Bao L, et al.
J Biol Chem
. 2016 Dec;
291(49):25762.
PMID: 27913663
No abstract available.
4.
Jokinen R, Marttinen P, Stewart J, Dear T, Battersby B
Hum Mol Genet
. 2015 Dec;
25(4):706-14.
PMID: 26681804
Mitochondria are dynamic organelles that divide and fuse by remodeling an outer and inner membrane in response to developmental, physiological and stress stimuli. These events are coordinated by conserved dynamin-related...
5.
Lawson M, McDonald M, Kovacic N, Khoo W, Terry R, Down J, et al.
Nat Commun
. 2015 Dec;
6:8983.
PMID: 26632274
Multiple myeloma is largely incurable, despite development of therapies that target myeloma cell-intrinsic pathways. Disease relapse is thought to originate from dormant myeloma cells, localized in specialized niches, which resist...
6.
Cahill T, Leo V, Kelly M, Stockenhuber A, Kennedy N, Bao L, et al.
J Biol Chem
. 2015 Sep;
290(43):25907-19.
PMID: 26370078
We have reported previously that a missense mutation in the mitochondrial fission gene Dynamin-related protein 1 (Drp1) underlies the Python mouse model of monogenic dilated cardiomyopathy. The aim of this...
7.
Haider M, Hunter K, Robinson S, Graham T, Corey E, Dear T, et al.
Bone
. 2015 Aug;
81:581-592.
PMID: 26279137
Introduction: Bone metastasis remains incurable with treatment restricted to palliative care. Cabozantinib (CBZ) is targeted against multiple receptor tyrosine kinases involved in tumour pathobiology, including hepatocyte growth factor receptor (MET)...
8.
Abraham S, Scarcia M, Bagshaw R, McMahon K, Grant G, Harvey T, et al.
Nat Commun
. 2015 Jul;
6:7286.
PMID: 26129894
During angiogenesis, Rho-GTPases influence endothelial cell migration and cell-cell adhesion; however it is not known whether they control formation of vessel lumens, which are essential for blood flow. Here, using...
9.
Li J, Hou B, Tumova S, Muraki K, Bruns A, Ludlow M, et al.
Nature
. 2014 Aug;
515(7526):279-282.
PMID: 25119035
The mechanisms by which physical forces regulate endothelial cells to determine the complexities of vascular structure and function are enigmatic. Studies of sensory neurons have suggested Piezo proteins as subunits...
10.
Haider M, Holen I, Dear T, Hunter K, Brown H
Bone
. 2014 Jun;
66:240-50.
PMID: 24971713
Introduction: Bone metastasis is the most common complication of advanced breast cancer. The associated cancer-induced bone disease is treated with bone-sparing agents like zoledronic acid. Clinical trials have shown that...