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T N Mayadas

Explore the profile of T N Mayadas including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 2059
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Recent Articles
1.
Mayadas T
Trends Cardiovasc Med . 2011 Jan; 5(4):149-57. PMID: 21232252
P-selectin is a leukocyte adhesion molecule present on the surfaces of activated platelets and endothelial cells. Its expression has been documented at sites of active inflammation including that resulting from...
2.
Coxon A, Cullere X, Knight S, Sethi S, Wakelin M, Stavrakis G, et al.
Immunity . 2001 Jun; 14(6):693-704. PMID: 11420040
Neutrophil accumulation is a hallmark of immune complex-mediated inflammatory disorders. Current models of neutrophil recruitment envision the capture of circulating neutrophils by activated endothelial cells. We now demonstrate that immobilized...
3.
van Spriel A, Leusen J, van Egmond M, Dijkman H, Assmann K, Mayadas T, et al.
Blood . 2001 Apr; 97(8):2478-86. PMID: 11290613
Receptors for human immunoglobulin (Ig)G and IgA initiate potent cytolysis of antibody (Ab)-coated targets by polymorphonuclear leukocytes (PMNs). Mac-1 (complement receptor type 3, CD11b/CD18) has previously been implicated in receptor...
4.
Ren Y, Stuart L, Lindberg F, Rosenkranz A, Chen Y, Mayadas T, et al.
J Immunol . 2001 Mar; 166(7):4743-50. PMID: 11254736
Neutrophils undergo constitutive death by apoptosis, leading to safe nonphlogistic phagocytosis and clearance by macrophages. Recent work has shown that before secondary necrosis, neutrophils exhibiting classical features of apoptosis can...
5.
Perera P, Mayadas T, Takeuchi O, Akira S, Goyert S, Vogel S
J Immunol . 2000 Dec; 166(1):574-81. PMID: 11123339
Overproduction of inflammatory mediators by macrophages in response to Gram-negative LPS has been implicated in septic shock. Recent reports indicate that three membrane-associated proteins, CD14, CD11b/CD18, and Toll-like receptor (TLR)...
6.
Barkalow F, Barkalow K, Mayadas T
Blood . 2000 Oct; 96(9):3070-7. PMID: 11049986
P-selectin is a leukocyte adhesion receptor stored in platelets and endothelial cells and is translocated to the surface upon cell activation. Purified P-selectin is oligomeric and has increased avidity for...
7.
Rosenkranz A, Knight S, Sethi S, Alexander S, COTRAN R, Mayadas T
Kidney Int . 2000 Sep; 58(3):1055-66. PMID: 10972670
Background: Several lines of evidence suggest that cellular immune mechanisms contribute to glomerulonephritis. Methods: The roles of alphabeta and gammadelta T cells in the pathogenesis of glomerulonephritis were investigated in...
8.
Yan J, Vetvicka V, Xia Y, Hanikyrova M, Mayadas T, Ross G
Immunopharmacology . 2000 Feb; 46(1):39-54. PMID: 10665778
Liver macrophages (Kupffer cells) play a major role in blood clearance of both C3-opsonized immune complexes and therapeutic beta-glucan polysaccharides. Human Kupffer cells express three types of C3-receptors: CR1 (C3b-receptor;...
9.
Coxon A, Tang T, Mayadas T
J Exp Med . 1999 Oct; 190(7):923-34. PMID: 10510082
The activation of endothelium is important in recruiting neutrophils to sites of inflammation and in modulating their function. We demonstrate that conditioned medium from cultured, activated endothelial cells acts to...
10.
Yan J, Vetvicka V, Xia Y, Coxon A, Carroll M, Mayadas T, et al.
J Immunol . 1999 Sep; 163(6):3045-52. PMID: 10477568
beta-Glucans were identified 36 years ago as a biologic response modifier that stimulated tumor rejection. In vitro studies have shown that beta-glucans bind to a lectin domain within complement receptor...