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T M Speight

Explore the profile of T M Speight including associated specialties, affiliations and a list of published articles. Areas
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Articles 127
Citations 2626
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Recent Articles
1.
Hinstridge V, Speight T
Drugs . 1991 Jan; 42 Suppl 2:8-20. PMID: 1718703
The high risk of subsequent mortality and morbidity following the occurrence of a myocardial infarction (MI) underlies the importance of instituting effective preventive regimens as part of the overall management...
2.
Brogden R, Heel R, Speight T, Avery G
Drugs . 1984 Oct; 28(4):292-323. PMID: 6386426
Piroxicam is a chemically different non-steroidal anti-inflammatory drug with a long half-life which enables it to be administered once daily. This member of the oxicam series of compounds is now...
3.
Chaffman M, Heel R, Brogden R, Speight T, Avery G
Drugs . 1984 Sep; 28(3):189-235. PMID: 6489195
Indapamide is an orally active sulphonamide diuretic agent. Although some evidence appears to indicate that the antihypertensive action of indapamide is primarily a result of its diuretic activity, only a...
4.
Brogden R, Heel R, Speight T, Avery G
Drugs . 1984 Aug; 28(2):99-126. PMID: 6381025
Inhaled beclomethasone dipropionate is now well established in the management of asthma. Studies conducted over the last decade, and since the drug was previously reviewed in the Journal, have confirmed...
5.
Ward A, Brogden R, Heel R, Speight T, Avery G
Drugs . 1984 Jul; 28(1):6-37. PMID: 6235105
Isotretinoin is a new orally active retinoic acid derivative for the treatment of severe refractory nodulocystic acne. The pharmacological profile of isotretinoin suggests that it acts primarily by reducing sebaceous...
6.
Richards D, Brogden R, Heel R, Speight T, Avery G
Drugs . 1984 Jul; 28(1):38-61. PMID: 6204835
Astemizole is an H1-histamine receptor antagonist with a long duration of action permitting once daily administration. Its efficacy in seasonal and perennial allergic rhinitis has been convincingly demonstrated, and several...
7.
Richards D, Heel R, Brogden R, Speight T, Avery G
Drugs . 1984 Jun; 27(6):469-527. PMID: 6329638
Ceftriaxone is a new 'third generation' semisynthetic cephalosporin with a long half-life which has resulted in a recommended once daily administration schedule. It is administered intravenously or intramuscularly and has...
8.
Chaffman M, Brogden R, Heel R, Speight T, Avery G
Drugs . 1984 May; 27(5):378-424. PMID: 6426923
Auranofin is the first orally active gold compound for the treatment of rheumatoid arthritis. Like other chrysotherapeutic agents, its exact mechanism of action is unknown, but it probably acts via...
9.
Holmes B, Heel R, Brogden R, Speight T, Avery G
Drugs . 1984 Apr; 27(4):301-27. PMID: 6373223
Gliclazide is a 'second generation' oral hypoglycaemic agent. The particular interest with this drug is that it has shown certain effects on the blood for which it is hoped there...
10.
Brogden R, Heel R, Speight T, Avery G
Drugs . 1984 Mar; 27(3):194-209. PMID: 6368184
Sucralfate is a basic aluminium salt of sulphated sucrose which is advocated for use in peptic ulcer disease. It is minimally absorbed after oral administration and is believed to act...