T M Mullen
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Explore the profile of T M Mullen including associated specialties, affiliations and a list of published articles.
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12
Citations
1245
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Recent Articles
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Llopis J, Westin S, Ricote M, Wang Z, Cho C, Kurokawa R, et al.
Proc Natl Acad Sci U S A
. 2000 Apr;
97(8):4363-8.
PMID: 10760302
Members of the nuclear receptor superfamily are thought to activate transcription by recruitment of one or more recently identified coactivator complexes. Here we demonstrate that both peroxisome proliferator-activated receptor binding...
3.
Li J, Tang H, Mullen T, Westberg C, Reddy T, Rose D, et al.
Proc Natl Acad Sci U S A
. 1999 Jan;
96(2):709-14.
PMID: 9892698
Retroviruses must bypass the tight coupling of splicing and nuclear export of mRNA in their replication cycle because unspliced genomic RNA and incompletely spliced mRNA must be exported to the...
4.
McInerney E, Rose D, FLYNN S, Westin S, Mullen T, Krones A, et al.
Genes Dev
. 1998 Nov;
12(21):3357-68.
PMID: 9808623
Ligand-dependent activation of gene transcription by nuclear receptors is dependent on the recruitment of coactivators, including a family of related NCoA/SRC factors, via a region containing three helical domains sharing...
5.
Xu L, Lavinsky R, Dasen J, FLYNN S, McInerney E, Mullen T, et al.
Nature
. 1998 Sep;
395(6699):301-6.
PMID: 9751061
POU-domain proteins, such as the pituitary-specific factor Pit-1, are members of the homeodomain family of proteins which are important in development and homeostasis, acting constitutively or in response to signal-transduction...
6.
Laherty C, Billin A, Lavinsky R, Yochum G, Bush A, Sun J, et al.
Mol Cell
. 1998 Aug;
2(1):33-42.
PMID: 9702189
The transcriptional corepressor mSin3 is found in a large multiprotein complex containing the histone deacetylases HDAC1 and HDAC2, in addition to at least five tightly associated polypeptides. We have cloned...
7.
Lavinsky R, Jepsen K, Heinzel T, Torchia J, Mullen T, Schiff R, et al.
Proc Natl Acad Sci U S A
. 1998 Apr;
95(6):2920-5.
PMID: 9501191
Several lines of evidence indicate that the nuclear receptor corepressor (N-CoR) complex imposes ligand dependence on transcriptional activation by the retinoic acid receptor and mediates the inhibitory effects of estrogen...
8.
Korzus E, Torchia J, Rose D, Xu L, Kurokawa R, McInerney E, et al.
Science
. 1998 Feb;
279(5351):703-7.
PMID: 9445475
Different classes of mammalian transcription factors-nuclear receptors, cyclic adenosine 3',5'-monophosphate-regulated enhancer binding protein (CREB), and signal transducer and activator of transcription-1 (STAT-1)-functionally require distinct components of the coactivator complex, including...
9.
Heinzel T, Lavinsky R, Mullen T, Soderstrom M, Laherty C, Torchia J, et al.
Nature
. 1997 May;
387(6628):43-8.
PMID: 9139820
Transcriptional repression by nuclear receptors has been correlated to binding of the putative co-repressor, N-CoR. A complex has been identified that contains N-CoR, the Mad presumptive co-repressor mSin3, and the...
10.
Eichhorst A, Janken J, Mullen T
Online J Knowl Synth Nurs
. 1997 Apr;
4:2.
PMID: 12876659
Studies bearing on the therapeutic value of cranberries in the prevention and/or treatment of urinary tract infections are reviewed. Research results are grouped to address the following questions: 1) Does...