T L Walunas
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Explore the profile of T L Walunas including associated specialties, affiliations and a list of published articles.
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12
Citations
2209
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Recent Articles
1.
Walunas T, Wang B, Wang C, Leiden J
J Immunol
. 2000 Mar;
164(6):2857-60.
PMID: 10706669
Ets1-deficient mice develop B and T cells but display a severe defect in the development of the NK cell lineage. In this report, we demonstrate that Ets1 is also required...
2.
Barton K, Muthusamy N, Fischer C, Ting C, Walunas T, Lanier L, et al.
Immunity
. 1998 Nov;
9(4):555-63.
PMID: 9806641
In this report we have investigated the role of the Ets-1 transcription factor in the differentiation of the NK cell lineage in mice. Splenic NK cells express high levels of...
3.
Walunas T, Bluestone J
J Immunol
. 1998 Apr;
160(8):3855-60.
PMID: 9558090
Cytotoxic T lymphocyte Ag-4 (CTLA-4; CD152) is an important T cell regulatory molecule. In vitro experiments have shown that the blockade of signals through CTLA-4 augments T cell expansion, while...
4.
Karandikar N, Vanderlugt C, Walunas T, Miller S, Bluestone J
J Exp Med
. 1996 Aug;
184(2):783-8.
PMID: 8760834
CTLA-4, a CD28 homologue expressed on activated T cells, binds with high affinity to the CD28 ligands, B7-1 (CD80) and B7-2 (CD86). This study was designed to examine the role...
5.
Walunas T, Bakker C, Bluestone J
J Exp Med
. 1996 Jun;
183(6):2541-50.
PMID: 8676075
CTLA-4 is a CD28 homologue believed to be a negative regulator of T cell function. However, the mechanism of this downregulatory activity is not well understood. The present study was...
6.
Walunas T, Sperling A, Khattri R, Thompson C, Bluestone J
J Immunol
. 1996 Feb;
156(3):1006-13.
PMID: 8557973
Thymocyte development requires positive selection of clones that can recognize Ag presented by MHC molecules and negative selection of clones that are self-reactive. However, the costimulatory signals required for negative...
7.
Lenschow D, Walunas T, Bluestone J
Annu Rev Immunol
. 1996 Jan;
14:233-58.
PMID: 8717514
T cells play a central role in the initiation and regulation of the immune response to antigen. Both the engagement of the TCR with MHC/Ag and a second signal are...
8.
Walunas T, Bruce D, Dustin L, Loh D, Bluestone J
J Immunol
. 1995 Aug;
155(4):1873-83.
PMID: 7543536
This study examined long-term phenotypic and functional effects of TCR ligation in vivo. Flow cytometric analysis of T cells from mice treated with anti-CD3 revealed an increase in CD44 expression...
9.
Kearney E, Walunas T, Karr R, Morton P, Loh D, Bluestone J, et al.
J Immunol
. 1995 Aug;
155(3):1032-6.
PMID: 7543510
The importance of CD28 costimulation to a primary T cell response in vivo was assessed in an adoptive transfer system where a small population of peptide-specific CD4+ TCR transgenic T...
10.
Green J, Noel P, Sperling A, Walunas T, Lenschow D, Stack R, et al.
Proc Assoc Am Physicians
. 1995 Apr;
107(1):41-6.
PMID: 8630743
No abstract available.