T L Tuan
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Explore the profile of T L Tuan including associated specialties, affiliations and a list of published articles.
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23
Citations
550
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Recent Articles
1.
Chun J, Tuan T, Han B, Vangsness C, Nimni M
Connect Tissue Res
. 2003 May;
44(2):81-7.
PMID: 12745674
The cellular properties of anterior cruciate ligament (ACL) and medial collateral ligament (MCL) fibroblasts have been analyzed in a three-dimensional fibrin matrix gel (FMG) system. The MCL fibroblasts proliferated significantly...
2.
Han Y, Tuan T, Hughes M, Wu H, Garner W
J Biol Chem
. 2001 Apr;
276(25):22341-50.
PMID: 11297541
Both cytokines and matrix metalloproteinases (MMPs) are active during physiologic and pathologic processes such as cancer metastasis and wound repair. We have systematically studied cytokine-mediated MMP regulation. Cytokine-mediated proteinase induction...
3.
Han Y, Tuan T, Wu H, Hughes M, Garner W
J Cell Sci
. 2000 Dec;
114(Pt 1):131-139.
PMID: 11112697
Tumor necrosis factor-alpha (TNF-(alpha)) is an important mediator during the inflammatory phase of wound healing. Excessive amounts of pro-inflammatory cytokines such as TNF-(alpha) are associated with inflammatory diseases including chronic...
4.
Island E, Wu H, Warburton D, Anderson K, Tuan T
Wound Repair Regen
. 2000 Jan;
7(6):467-76.
PMID: 10633006
To investigate developmental differences in the wound repair process between fetal and adult skin fibroblasts, we studied the expression of plasminogen activator, plasminogen activator inhibitor, matrix metalloproteinase, and tissue inhibitor...
5.
Wysocki A, Kusakabe A, Chang S, Tuan T
Wound Repair Regen
. 1999 Jul;
7(3):154-65.
PMID: 10417751
The plasminogen activator/plasmin system is known to initiate a proteolytic cascade resulting in the activation of matrix metalloproteinases in vitro leading to the degradation of extracellular matrix. To investigate whether...
6.
Coleman C, Tuan T, Buckley S, Anderson K, Warburton D
Pediatr Res
. 1998 Mar;
43(3):403-9.
PMID: 9505281
The early fetus responds to cutaneous wounds in a fundamentally different way from the adult; fetal wounds heal without scars. Wound contraction is a vital component of wound healing. The...
7.
Tuan T, Nichter L
Mol Med Today
. 1998 Mar;
4(1):19-24.
PMID: 9494966
Excess scar formation secondary to traumatic or surgical injuries can have devastating consequences, ranging from body disfigurement to organ dysfunction. Hypertrophic scars and keloids are skin fibrotic conditions that can...
8.
Ashizawa N, Graf K, Do Y, Nunohiro T, Giachelli C, Meehan W, et al.
J Clin Invest
. 1996 Nov;
98(10):2218-27.
PMID: 8941637
Angiotensin II (AII) is a critical factor in cardiac remodeling which involves hypertrophy, fibroblast proliferation, and extracellular matrix production. However, little is known about the mechanism by which AII accelerates...
9.
Younai S, Venters G, Vu S, Nichter L, Nimni M, Tuan T
Ann Plast Surg
. 1996 May;
36(5):495-501.
PMID: 8743660
Excessive scar contracture by wound fibroblasts can have devastating consequences, ranging from body disfigurement to joint immobility. The ability of fibroblasts isolated from lesions of hypertrophic scars, keloids, normal skin,...
10.
Tuan T, Zhu J, Sun B, Nichter L, Nimni M, Laug W
J Invest Dermatol
. 1996 May;
106(5):1007-11.
PMID: 8618030
Using a 3-dimensional fibrin gel model system simulating fibroplasia of wound repair, we investigated the interaction between keloid fibroblasts and fibrin matrix and compared it with that of normal fibroblasts....