T J Graddis
Overview
Explore the profile of T J Graddis including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
122
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Diegel M, Chen F, Laus R, Graddis T, Vidovic D
Scand J Immunol
. 2003 Jun;
58(1):1-8.
PMID: 12828552
Proteins in their native form are incapable of stimulating antigen (Ag)-specific T cells, which can only recognize major histocompatibility complex (MHC)-bound peptides that have been generated by intracellular processing within...
2.
Graddis T, Remmele Jr R, McGrew J
Curr Pharm Biotechnol
. 2002 Dec;
3(4):285-97.
PMID: 12463413
Therapeutic proteins have been engineered for a variety of purposes including reduced antigenicity, longer half-life, simplified process development, and increased affinity. Fusion proteins bring together functions from two different molecules...
3.
Laus R, Graddis T, Hakim I, Vidovic D
Nat Biotechnol
. 2000 Dec;
18(12):1269-72.
PMID: 11101805
Soluble extracellular protein antigens are notoriously poor stimulators of CD8+ cytotoxic T-lymphocyte (CTL) responses, largely because these antigens have inefficient access to an endogenous cytosolic pathway of the major histocompatibility...
4.
Graddis T, Brasel K, Friend D, Srinivasan S, Wee S, Lyman S, et al.
J Biol Chem
. 1998 Jul;
273(28):17626-33.
PMID: 9651358
FLT3 ligand (FLT3L) stimulates primitive hematopoietic cells by binding to and activating the FLT3 receptor (FLT3R). We carried out a structure-activity study of human FLT3L in order to define the...
5.
Graddis T, Myszka D, Chaiken I
Biochemistry
. 1993 Nov;
32(47):12664-71.
PMID: 8251485
Sequence-simplified coiled coil polypeptides were synthesized and their folding properties characterized in order to define the role of charged border residues at the coiled coil interface for the controlled formation...
6.
Adams M, Wagner L, Graddis T, Landick R, Antonucci T, Gibson A, et al.
J Biol Chem
. 1990 Jul;
265(20):11436-43.
PMID: 2195019
The nucleotide sequence of the genes encoding the high affinity, branched-chain amino acid transport systems LIV-I and LS has been determined. Seven genes are present on a 7568-base pair DNA...
7.
Graddis T, Klig L, Yanofsky C, OXENDER D
Proteins
. 1988 Jan;
4(3):173-81.
PMID: 3070558
Availability of the three-dimensional structure of the trp repressor of Escherichia coli and a large group of repressor mutants has permitted the identification and analysis of mutants with substitutions of...