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D L OXENDER

Explore the profile of D L OXENDER including associated specialties, affiliations and a list of published articles. Areas
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Articles 103
Citations 1602
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Recent Articles
1.
Wang M, Offord J, OXENDER D, Su T
Biochem J . 1999 Aug; 342 ( Pt 2):313-20. PMID: 10455017
Gabapentin [Neurontin, 1-(aminomethyl)cyclohexaneacetic acid] is a novel anticonvulsant drug with a high binding affinity for the Ca(2+)-channel subunit alpha(2)delta. In this study, the gabapentin-binding properties of wild-type and mutated porcine...
2.
Chung F, Wu L, Lee H, Mueller W, Spahr M, Eaton S, et al.
Protein Expr Purif . 1998 Jul; 13(2):222-8. PMID: 9675066
Elevated plasma lipoprotein(a) [Lp(a)] is an independent risk factor for several vascular diseases. Lp(a) particles are generated through the formation of a disulfide bond between Cys4057 of kringle IV type...
3.
Su T, Wang M, OXENDER D, Saltiel A
Endocrinology . 1998 Mar; 139(3):832-7. PMID: 9492010
System A is one of the most highly regulated transport systems for transport of neutral amino acids into mammalian cells. Stimulation of uptake of alpha-[3H]methylaminoisobutyric acid (MeAIB), a nonmetabolizable system...
4.
Su T, Wang M, Syu L, Saltiel A, OXENDER D
J Biol Chem . 1998 Mar; 273(6):3173-9. PMID: 9452428
The insulin-stimulated uptake of 2-(methylamino)isobutyric acid (MeAIB), a nonmetabolizable substrate for system A, in 3T3-L1 adipocytes was investigated. As cells took on a more adipogenic phenotype, the insulin-stimulated versus the...
5.
Su T, Campbell G, OXENDER D
Brain Res . 1997 May; 757(1):69-78. PMID: 9200500
In the present study, uptake of glutamine by rat cerebellar granule cells, a predominantly glutamatergic nerve cell population, has been investigated. Glutamine is taken up by granule cells via at...
6.
Tian Y, Wu L, OXENDER D, Chung F
J Biol Chem . 1996 Aug; 271(34):20250-7. PMID: 8702757
Three chimeric receptors were constructed by exchanging exon sequences between human NK1 and NK3 receptor genes. The resulting chimeric receptors not only retained high affinities for their natural ligands substance...
7.
Goldlust A, Su T, Welty D, Taylor C, OXENDER D
Epilepsy Res . 1995 Sep; 22(1):1-11. PMID: 8565962
Gabapentin is a novel anticonvulsant drug. The anticonvulsant mechanism of gabapentin is not known. Based on the amino acid structure of gabapentin we explored its possible effects on glutamate and...
8.
Su T, Lunney E, Campbell G, OXENDER D
J Neurochem . 1995 May; 64(5):2125-31. PMID: 7722496
The system L transporter is generally considered to be one of the major Na(+)-independent carriers for large neutral alpha-amino acids in mammalian cells. However, we found that cultured astrocytes from...
9.
Collarini E, Campbell G, OXENDER D
J Cell Biochem . 1994 Dec; 56(4):544-9. PMID: 7890812
We have used the technique of somatic cell hybridization to study the regulation of the neutral amino acid transport system L in Chinese hamster ovary (CHO) cells. The cell line...
10.
Chung F, Wu L, Vartanian M, Watling K, Guard S, Woodruff G, et al.
Biochem Biophys Res Commun . 1994 Feb; 198(3):967-72. PMID: 8117304
SR 48968, a non-peptide tachykinin NK2 receptor antagonist, has been shown to possess sub-micromolar affinity for NK3 receptors present in the guinea pig. In the present study, we have compared...