T G Parslow
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Explore the profile of T G Parslow including associated specialties, affiliations and a list of published articles.
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49
Citations
2723
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Recent Articles
1.
Majeti R, Xu Z, Parslow T, Olson J, Daikh D, Killeen N, et al.
Cell
. 2001 Feb;
103(7):1059-70.
PMID: 11163182
A model has been proposed for the regulation of CD45, and by homology other RPTPs, in which dimerization inhibits phosphatase activity through symmetrical interactions between an inhibitory structural wedge and...
2.
Fitch M, Chang C, Parslow T
Cell Death Differ
. 2000 Apr;
7(4):338-49.
PMID: 10773818
Bax causes apoptosis by associating with mitochondria and triggering cytochrome c release, which activates the caspase cascade. Bax can also kill some cells independently of caspases, but the requirements for...
3.
Doria M, Salcini A, Colombo E, Parslow T, Pelicci P, Di Fiore P
J Cell Biol
. 1999 Dec;
147(7):1379-84.
PMID: 10613896
The Eps15 homology (EH) module is a protein-protein interaction domain that establishes a network of connections involved in various aspects of endocytosis and sorting. The finding that EH-containing proteins bind...
4.
Clever J, Taplitz R, Lochrie M, Polisky B, Parslow T
J Virol
. 1999 Dec;
74(1):541-6.
PMID: 10590146
Retroviral RNA encapsidation depends on the specific binding of Gag proteins to packaging (psi) signals in genomic RNA. We investigated whether an in vitro-selected, high-affinity RNA ligand for the nucleocapsid...
5.
Mujeeb A, Parslow T, Zarrinpar A, Das C, James T
FEBS Lett
. 1999 Nov;
458(3):387-92.
PMID: 10570946
The two identical genomic RNA strands inside each HIV-1 viral particle are linked through homodimerization of an RNA stem-loop, termed SL1, near their 5' ends. SL1 first dimerizes through a...
6.
Clever J, Eckstein D, Parslow T
J Virol
. 1998 Dec;
73(1):101-9.
PMID: 9847312
The efficient packaging of genomic RNA into virions of human immunodeficiency virus type 1 (HIV-1) is directed by cis-acting encapsidation signals, which have been mapped to particular RNA stem-loop structures...
7.
Mujeeb A, Clever J, Billeci T, James T, Parslow T
Nat Struct Biol
. 1998 Jun;
5(6):432-6.
PMID: 9628479
Retroviral genomes must dimerize to be fully infectious. Dimerization is directed by a unique RNA hairpin structure with a palindrome in its loop: hairpins of two strands first associate transiently...
8.
Lochrie M, Waugh S, Pratt Jr D, Clever J, Parslow T, Polisky B
Nucleic Acids Res
. 1997 Jul;
25(14):2902-10.
PMID: 9207041
RNA ligands that bind to the human immunodeficiency virus type-1 (HIV-1) gag polyprotein with 10(-9) M affinity were isolated from a complex pool of RNAs using an in vitro selection...
9.
Mutant human immunodeficiency virus type 1 genomes with defects in RNA dimerization or encapsidation
Clever J, Parslow T
J Virol
. 1997 May;
71(5):3407-14.
PMID: 9094610
Retrovirus particles each contain two copies of the viral genome in the form of a noncovalently linked RNA dimer. Earlier studies have mapped a cis-acting region near the 5' end...
10.
Lee L, Hunter J, Mujeeb A, Turck C, Parslow T
J Biol Chem
. 1996 Sep;
271(38):23284-8.
PMID: 8798527
A region occupying approximately 24 amino acids near the N terminus of human Bcl2 is essential for this cytoplasmic membrane protein's ability to inhibit apoptosis. Systematic mutagenesis of this N-terminal...