T J Hope
Overview
Explore the profile of T J Hope including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
48
Citations
2991
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Schommers P, Martrus G, Matschl U, Sirignano M, Lutgehetmann M, Richert L, et al.
J Virol
. 2016 Jun;
90(16):7579-7586.
PMID: 27279617
Unlabelled: HIV-1-infected individuals with protective HLA class I alleles exhibit better control of viremia and slower disease progression. Virus control in these individuals has been associated with strong and potent...
2.
Veazey R, Pilch-Cooper H, Hope T, Alter G, Carias A, Sips M, et al.
Mucosal Immunol
. 2016 Feb;
9(6):1528-1536.
PMID: 26838048
Understanding vaginal and rectal HIV transmission and protective cellular and molecular mechanisms is critical for designing new prevention strategies, including those required for an effective vaccine. The determinants of protection...
3.
Shukair S, Allen S, Cianci G, Stieh D, Anderson M, Baig S, et al.
Mucosal Immunol
. 2012 Sep;
6(2):427-34.
PMID: 22990624
Cervical and vaginal epithelia are primary barriers against HIV type I (HIV-1) entry during male-to-female transmission. Cervical mucus (CM) is produced by the endocervix and forms a layer locally as...
4.
Fahrbach K, Barry S, Anderson M, Hope T
Mucosal Immunol
. 2010 Apr;
3(4):410-8.
PMID: 20410876
The decrease in HIV acquisition after circumcision suggests a role for the foreskin in HIV transmission. However, the mechanism leading to protection remains undefined. Using tissue explant cultures we found...
5.
Zanta-Boussif M, Charrier S, Brice-Ouzet A, Martin S, Opolon P, Thrasher A, et al.
Gene Ther
. 2009 Mar;
16(5):605-19.
PMID: 19262615
The woodchuck hepatitis virus posttranscriptional regulatory element (WPRE) is widely used in retroviral gene transfer vectors. However, this element contains an open-reading frame (ORF) encoding a truncated peptide of the...
6.
Anderson J, Hope T
Gene Ther
. 2005 Nov;
12(23):1667-78.
PMID: 16292352
Retroviruses are efficient vehicles for delivering transgenes in vivo. Their ability to integrate into the host genome, providing a permanent imprint of their genes in the host, is a key...
7.
Campbell E, Hope T
Gene Ther
. 2005 Sep;
12(18):1353-9.
PMID: 16151445
The intracellular steps involved in viral infection, namely cytoplasmic trafficking and nuclear import, are critical events in the viral life cycle that have lagged behind other areas of viral research....
8.
Harris M, Hope T
Essays Biochem
. 2002 Dec;
36:115-27.
PMID: 12471907
The retroviruses export intron-containing RNA. The complex retroviruses encode a Rev protein that uses a leucine-rich NES to interact with CRM1 and the U snRNA-export pathway. Other viruses encode proteins...
9.
10.
Gupta K, Ott D, Hope T, Siliciano R, Boeke J
J Virol
. 2000 Nov;
74(24):11811-24.
PMID: 11090181
Active nuclear import of the human immunodeficiency virus type 1 (HIV-1) preintegration complex (PIC) is essential for the productive infection of nondividing cells. Nuclear import of the PIC is mediated...