T E DeCoursey
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Explore the profile of T E DeCoursey including associated specialties, affiliations and a list of published articles.
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53
Citations
2154
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Recent Articles
1.
Smith R, Morgan D, Sharma L, Cherny V, Tidswell N, Molo M, et al.
Hum Reprod
. 2019 Oct;
34(10):1974-1983.
PMID: 31633762
Study Question: Do human oocytes express voltage-gated proton channels? Summary Answer: Human oocytes exhibit voltage-gated proton currents. What Is Known Already: Voltage-gated proton currents have been reported in human sperm,...
2.
DeCoursey T
Cell Mol Life Sci
. 2008 May;
65(16):2554-73.
PMID: 18463791
The history of research on voltage-gated proton channels is recounted, from their proposed existence in dinoflagellates by Hastings in 1972 and their demonstration in snail neurons by Thomas and Meech...
3.
Musset B, Cherny V, Morgan D, Okamura Y, Ramsey I, Clapham D, et al.
J Physiol
. 2008 Mar;
586(10):2477-86.
PMID: 18356202
Two years ago, genes coding for voltage-gated proton channels in humans, mice and Ciona intestinalis were discovered. Transfection of cDNA encoding the human HVCN1 (H(V)1) or mouse (mVSOP) ortholog of...
4.
DeCoursey T, Ligeti E
Cell Mol Life Sci
. 2005 Sep;
62(19-20):2173-93.
PMID: 16132232
NADPH oxidase of phagocytes plays a crucial role in host defense by producing reactive oxygen species (ROS) that are intended to kill invading microbes. Many other cells produce ROS for...
5.
Cherny V, Henderson L, Xu W, Thomas L, DeCoursey T
J Physiol
. 2001 Sep;
535(Pt 3):783-94.
PMID: 11559775
1. Effects of arachidonic acid (AA) on proton and electron currents in human eosinophils were studied using the permeabilized-patch voltage-clamp technique, using an applied NH4+ gradient to control pH(i). 2....
6.
DeCoursey T, Cherny V, DeCoursey A, Xu W, Thomas L
J Physiol
. 2001 Sep;
535(Pt 3):767-81.
PMID: 11559774
1. Proton and electron currents in human eosinophils were studied using the permeabilized-patch voltage-clamp technique, with an applied NH4+ gradient to control pH(i). 2. Voltage-gated proton channels in unstimulated human...
7.
DeCoursey T, Cherny V, Morgan D, Katz B, Dinauer M
J Biol Chem
. 2001 Jul;
276(39):36063-6.
PMID: 11477065
During the "respiratory burst," the NADPH oxidase complex of phagocytes produces reactive oxygen species that kill bacteria and other invaders (Babior, B. M. (1999) Blood 93, 1464-1476). Electron efflux through...
8.
Eder C, DeCoursey T
Prog Neurobiol
. 2001 Mar;
64(3):277-305.
PMID: 11240310
Microglia, macrophages that reside in the brain, can express at least 12 different ion channels, including voltage-gated proton channels. The properties of H+ currents in microglia are similar to those...
9.
Schilling T, Quandt F, Cherny V, Zhou W, Heinemann U, DeCoursey T, et al.
Am J Physiol Cell Physiol
. 2000 Sep;
279(4):C1123-34.
PMID: 11003593
Microglial activation is accompanied by changes in K(+) channel expression. Here we demonstrate that a deactivating cytokine changes the electrophysiological properties of microglial cells. Upregulation of delayed rectifier (DR) K(+)...
10.
DeCoursey T, Cherny V, Zhou W, Thomas L
Proc Natl Acad Sci U S A
. 2000 May;
97(12):6885-9.
PMID: 10823889
Generation of reactive oxygen species by the NADPH oxidase complex is an important bactericidal weapon of phagocytes. Phorbol myristate acetate (PMA) is a potent agonist for this "respiratory burst" in...