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T D Tsai

Explore the profile of T D Tsai including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 87
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Recent Articles
1.
Wood L, Tsai T, Lee K, Vogeli G
Gene . 1995 Oct; 163(2):313-7. PMID: 7590287
We have isolated a cDNA clone encoding a human inward rectifier potassium channel (hIRK1). The nucleotide (nt) sequence of the coding region is 88% similar to the mouse clone with...
2.
Tsai T, Barish M
J Neurobiol . 1995 Jun; 27(2):252-65. PMID: 7658204
To gain a better understanding of Ca(2+)-induced Ca2+ release in central neurons, we have studied the increase in intracellular Ca2+ concentration ([Ca2+]i) induced by application of caffeine to cells cultured...
3.
Tsai T, Shuck M, Thompson D, Bienkowski M, Lee K
Am J Physiol . 1995 May; 268(5 Pt 1):C1173-8. PMID: 7762610
The pH sensitivity of a cloned rat kidney K+ channel, ROMK1, was examined after expression in Xenopus oocytes. Membrane currents and intracellular pH (pHi) were concomitantly monitored by the two-microelectrode...
4.
Xu X, Tsai T, Wang J, Lee E, Lee K
J Pharmacol Exp Ther . 1994 Oct; 271(1):362-9. PMID: 7965736
The effects of the cardioprotective, vasorelaxant agent NS-004 [1-(2'-hydroxy-5'-chlorophenyl)-5-trifluoromethyl-2(3H) benzimidazolone] on K+ currents of freshly isolated canine coronary artery smooth muscle cells were examined using the suction pipette method. The...
5.
Shuck M, Bock J, Benjamin C, Tsai T, Lee K, Slightom J, et al.
J Biol Chem . 1994 Sep; 269(39):24261-70. PMID: 7929082
The rat kidney ROM-K1 potassium channel cDNA was used to clone the homolog from human kidney using a combination of cDNA cloning, reverse transcriptase-polymerase chain reaction (RT-PCR), and primer extension...
6.
Xu X, Tsai T, Lee K
J Pharmacol Exp Ther . 1993 Aug; 266(2):978-84. PMID: 8394925
The specific activity of a pyridylcyanoguanidine, P-1075, on cardiac potassium current inhibited by internal ATP (KATP) was examined using whole-cell and single-channel recording techniques. At 10 microM, the compound markedly...
7.
Lee K, Tsai T, Lee E
Eur J Pharmacol . 1993 Mar; 234(1):43-53. PMID: 8472760
This study compares the membrane activity of ibutilide, d-sotalol, sematilide, E-4031 and dofetilide on single ventricular cells under identical experimental conditions. We found that ibutilide and dofetilide produced a 'bell-shaped'...
8.
Liu Q, Tsai T
Sheng Li Xue Bao . 1990 Jun; 42(3):254-61. PMID: 2082470
The sodium channels of dissociated single ventricular cells of adult guinea pig heart were inactivated by partial depolarization in high K+ (25 mmol/L) Tyrode's solution and slow response action potential...
9.
Chen X, Tsai T
Sheng Li Xue Bao . 1989 Oct; 41(5):428-35. PMID: 2557674
Effects of ethanol, butanol, hexanol and octanol on slow action potential (APA, APD50, Vmax, and V'max) and its correspondent ICa (Imax) and Ik (I'max) of guinea-pig papillary muscle were measured...
10.
Dai Z, Tsai T
Sheng Li Xue Bao . 1987 Aug; 39(4):334-42. PMID: 3686053
No abstract available.