T C Spelsberg
Overview
Explore the profile of T C Spelsberg including associated specialties, affiliations and a list of published articles.
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216
Citations
3406
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Recent Articles
1.
2.
Subramaniam M, Hawse J, Bruinsma E, Grygo S, Cicek M, Oursler M, et al.
Biochem Biophys Res Commun
. 2010 Jan;
392(1):72-6.
PMID: 20059964
TGFbeta inducible early gene-1 (TIEG) is a member of the Krüppel-like family of transcription factors (KLF10) that plays an important role in TGFbeta mediated Smad signaling. In order to better...
3.
Hawse J, Iwaniec U, Bensamoun S, Monroe D, Peters K, Ilharreborde B, et al.
Bone
. 2008 Apr;
42(6):1025-31.
PMID: 18396127
TGFbeta inducible early gene-1 (TIEG) was originally cloned from human osteoblasts (OB) and has been shown to play an important role in TGFbeta/Smad signaling, regulation of gene expression and OB...
4.
Modder U, Sanyal A, Xu J, OMalley B, Spelsberg T, Khosla S
Bone
. 2007 Dec;
42(2):414-21.
PMID: 18055287
Estrogen (E) is critical for the maintenance of bone mass in both female and male mice and steroid receptor coactivator (SRC)-1 has been shown to be important for mediating E...
5.
Hawse J, Subramaniam M, Ingle J, Oursler M, Rajamannan N, Spelsberg T
J Cell Biochem
. 2007 Jun;
103(2):383-92.
PMID: 17541956
It is well established that E(2) and TGFbeta have major biological effects in multiple tissues, including bone. The signaling pathways through which these two factors elicit their effects are well...
6.
Maran A, Shogren K, Zhang M, Yaszemski M, Hefferan T, Spelsberg T, et al.
Bone
. 2006 May;
39(3):523-9.
PMID: 16707283
Tibolone is a synthetic steroid which undergoes tissue selective metabolism into several metabolites having estrogenic, progestogenic or androgenic activities. The effects of 3 alpha-hydroxy tibolone (Org 4094), 3 beta-hydroxy tibolone...
7.
Tsubone T, Moran S, Subramaniam M, Amadio P, Spelsberg T, An K
J Orthop Res
. 2006 Feb;
24(3):569-75.
PMID: 16463363
The role of transforming growth factor beta (TGF-beta) in tendon healing is still not clearly established. TGF-beta affects gene expression primarily through the activation of the Smad signaling pathway. The...
8.
Rajamannan N, Subramaniam M, Stock S, Stone N, Springett M, Ignatiev K, et al.
Heart
. 2005 May;
91(6):806-10.
PMID: 15894785
Objective: To study in a rabbit model the expression of endothelial nitric oxide synthase (eNOS) in association with the development of calcification of the aortic valve, and to assess the...
9.
Monroe D, Secreto F, Spelsberg T
J Musculoskelet Neuronal Interact
. 2005 Mar;
3(4):357-62.
PMID: 15758323
No abstract available.
10.
Sanyal A, Riggs B, Spelsberg T, Khosla S
J Cell Biochem
. 2004 Nov;
94(1):88-97.
PMID: 15517596
Estrogen plays a critical role in bone metabolism in both sexes. While the major action of estrogen is to inhibit bone resorption, it is now clear that early osteoblastic (or...