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D S Colvard

Explore the profile of D S Colvard including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 385
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Recent Articles
1.
Nativ O, Umehara T, Colvard D, Therneau T, Farrow G, Spelsberg T, et al.
Eur Urol . 1997 Jan; 32(1):96-9. PMID: 9266239
Objective: To evaluate the relationship between the nuclear DNA content and the tissue estrogen receptor (ER) level in patients with operable adenocarcinoma of the prostate. Method: Surgical specimens taken from...
2.
Keeting P, Scott R, Colvard D, Anderson M, Oursler M, Spelsberg T, et al.
J Bone Miner Res . 1992 Feb; 7(2):127-36. PMID: 1373929
A new bone cell line was established by transfecting normal adult human osteoblast-like (hOB) cells, derived from a 68-year-old woman, with the plasmid pSV3 neo. The plasmid included coding sequences...
3.
Keeting P, Rifas L, Harris S, Colvard D, Spelsberg T, Peck W, et al.
J Bone Miner Res . 1991 Aug; 6(8):827-33. PMID: 1785373
To determine if bone cells produce interleukin-1 beta (IL-1 beta), a potent bone resorption-stimulating agent, we studied well-characterized, nearly homogeneous cultures of normal human osteoblast-like (hOB) cells. With four strains...
4.
Keeting P, Scott R, Colvard D, Han I, Spelsberg T, Riggs B
J Bone Miner Res . 1991 Mar; 6(3):297-304. PMID: 2035356
Although osteoblasts contain estrogen receptors, it is unclear whether estrogen has direct effects on osteoblast proliferation and differentiation. We evaluated the effects of 17 beta-estradiol treatment (1 pM to 10...
5.
Turner R, Colvard D, Spelsberg T
Endocrinology . 1990 Sep; 127(3):1346-51. PMID: 2387257
Estrogen is important for both the sexual dimorphism of the skeleton during growth and the maintenance of bone balance in adults. This report describes the in vivo effects of estrogen...
6.
Turner R, Bleiberg B, Colvard D, Keeting P, Evans G, Spelsberg T
J Bone Miner Res . 1990 Jul; 5(7):775-9. PMID: 2396504
Periosteal cells were isolated from tibiae of adult male rats after collagenase treatment. Northern blot analysis of total cytoplasmic RNA extracted from the isolated periosteal cells was positive for expression...
7.
Colvard D, Graham M, Berg N, Ingle J, Schaid D, Podratz K, et al.
Recent Results Cancer Res . 1990 Jan; 118:233-41. PMID: 1700456
A nuclear binding assay was developed for the purpose of having available a more predictive assay for hormone responsiveness in human cancers. The BNB assay identified specific and saturable steroid...
8.
Berg N, Colvard D, Neel 3rd H, Weiland L, Spelsberg T
Otolaryngol Head Neck Surg . 1989 Nov; 101(5):527-36. PMID: 2512530
This study had three major goals: (1) to vigorously verify the presence of progesterone receptors in squamous cell carcinoma of the upper aerodigestive tract (HN-SCC). Antiprogesterone receptor monoclonal antibodies revealed...
9.
Halper J, Colvard D, Scheithauer B, JIANG N, Press M, Graham 2nd M, et al.
Neurosurgery . 1989 Oct; 25(4):546-52; discussion 552-3. PMID: 2477767
We studied the status of estrogen (ER) and progesterone (PR) receptors in meningiomas removed from 52 patients, comparing dextran-coated charcoal (DCC), nuclear binding (NB), and immunoperoxidase (IP) assays. Each of...
10.
Colvard D, Eriksen E, Keeting P, Wilson E, Lubahn D, French F, et al.
Proc Natl Acad Sci U S A . 1989 Feb; 86(3):854-7. PMID: 2915981
The sex steroids, androgens and estrogens, are major regulators of bone metabolism. However, whether these hormones act on bone cells through direct or indirect mechanisms has remained unclear. A nuclear...