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T C Chinet

Explore the profile of T C Chinet including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 105
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Recent Articles
1.
Roche N, Chinet T, Belouchi N, Julie C, Huchon G
Eur Respir J . 2000 Sep; 16(2):309-15. PMID: 10968508
Several epidemiological studies suggest that exposure to house dust mite allergens plays a role in the pathogenesis of asthma. Since many of these allergens exhibit enzymatic properties, they may damage...
2.
Roche N, El Husseini F, Labrune S, Giraud V, Chinet T, Huchon G
Chest . 1998 Jun; 113(6):1684-8. PMID: 9631813
Background: Nonspecific bronchial provocation tests may be simplified by the use of hand-held devices to deliver methacholine. Objective: To study the feasibility of using a metered-dose inhaler (MDI) to administer...
3.
Roche N, Chinet T, Huchon G
Eur Respir J . 1997 Mar; 10(3):719-26. PMID: 9073012
Asthma and allergy are extremely frequent diseases, affecting 5-10% and 30% of the population, respectively. The prevalence of asthma has increased in many developed countries, which may be due to...
4.
Chinet T, Gabriel S, Penland C, Sato M, Stutts M, Boucher R, et al.
Biochem Biophys Res Commun . 1997 Jan; 230(2):470-5. PMID: 9016805
Distal airways are believed to be a major site of disease in cystic fibrosis. The product of the CF gene, CFTR, is expressed in non-ciliated bronchiolar epithelial (Clara) cells. Clara...
5.
Van Scott M, Chinet T, Burnette A, Paradiso A
Am J Physiol . 1995 Jul; 269(1 Pt 1):L30-7. PMID: 7631811
Previous studies demonstrated that elevation of intracellular calcium concentration ([Ca2+]i) increased electrogenic anion transport by bronchiolar epithelia. Extracellular nucleotides were shown to elevate [Ca2+]i and transepithelial short-circuit current (Isc) in...
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Chinet T, Fullton J, Yankaskas J, Boucher R, Stutts M
Am J Physiol . 1994 Apr; 266(4 Pt 1):C1061-8. PMID: 7513953
Transepithelial Na+ absorption is increased two to three times in cystic fibrosis (CF) compared with normal (NL) airway epithelia. This increase has been associated with a higher Na+ permeability of...
8.
Chinet T, Fullton J, Yankaskas J, Boucher R, Stutts M
Am J Physiol . 1993 Oct; 265(4 Pt 1):C1050-60. PMID: 7694472
We used patch-clamp techniques to study the channels that underlie the Na+ conductance of the apical membrane of human normal nasal epithelial cells. Cells were cultured on permeable supports and...
9.
Chinet T
N Engl J Med . 1993 Sep; 329(13):967-8. PMID: 8361520
No abstract available.
10.
Stutts M, Chinet T, Mason S, Fullton J, Clarke L, Boucher R
Proc Natl Acad Sci U S A . 1992 Mar; 89(5):1621-5. PMID: 1371880
The rate of Cl- secretion by human airway epithelium is determined, in part, by apical cell membrane Cl- conductance. In cystic fibrosis airway epithelia, defective regulation of Cl- conductance decreases...