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Sylvia M LaCourse

Explore the profile of Sylvia M LaCourse including associated specialties, affiliations and a list of published articles. Areas
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Articles 63
Citations 715
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Recent Articles
1.
Saha A, Escudero J, Layouni T, Mecha J, Maleche-Obimbo E, Matemo D, et al.
Open Forum Infect Dis . 2025 Feb; 12(2):ofaf067. PMID: 39981072
Background: Pregnancy increases (Mtb) reactivation risk and alters immune responses. We assessed Mtb-specific CD4+ T-cell responses in pregnant women with HIV (WLHIV) and without, including those receiving isoniazid preventive therapy...
2.
Day C, Njuguna I, Cranmer L, Whatney W, Pearson R, Arlehamn C, et al.
J Infect Dis . 2024 Dec; PMID: 39693245
Background: Despite immune restoration after initiation of antiretroviral treatment (ART), the risk of tuberculosis (TB) persists in children living with HIV (CLHIV). We determined patterns of immune restoration of mycobacteria-specific...
3.
Rosen L, Thielking A, Dugdale C, Montepiedra G, Kalk E, Kim S, et al.
Clin Infect Dis . 2024 Nov; PMID: 39544107
Background: Although prior studies of tuberculosis-preventive treatment (TPT) for pregnant people with human immunodeficiency virus (PPWH) report conflicting adverse pregnancy outcome (APO) risks, international guidelines recommend TPT for PPWH. Methods:...
4.
Cherkos A, LaCourse S, Enquobahrie D, Escudero J, Mecha J, Matemo D, et al.
PLoS One . 2024 Aug; 19(8):e0293708. PMID: 39150949
Background: Isoniazid preventive therapy (IPT) decreases risk of tuberculosis (TB) disease; impact on long-term infant growth is unknown. In a recent randomized trial (RCT), we assessed IPT effects on infant...
5.
LaCourse S, Wetzler E, Aurelio M, Escudero J, Selke S, Greninger A, et al.
J Infect Dis . 2024 Jan; 229(4):1241-1243. PMID: 38285008
No abstract available.
6.
LaCourse S, Wetzler E, Aurelio M, Escudero J, Selke S, Greninger A, et al.
J Infect Dis . 2023 Dec; 229(6):1728-1739. PMID: 38128542
Background: Hybrid immunity (infection plus vaccination) may increase maternally derived SARS-CoV-2 antibody responses and durability versus infection alone. Methods: Prospective cohort of pregnant participants with prior SARS-CoV-2 infection (anti-nucleocapsid IgG,...
7.
Miele K, Rock R, LaCourse S, Ashkin D, Armitige L, Pomputius W, et al.
MMWR Morb Mortal Wkly Rep . 2023 Dec; 72(49):1331-1332. PMID: 38060433
No abstract available.
8.
Cherkos A, Cranmer L, Njuguna I, LaCourse S, Mugo C, Moraa H, et al.
AIDS . 2023 Nov; 38(4):579-588. PMID: 38016160
Objective: Evaluate effects of tuberculosis (TB)-HIV co-treatment on clinical and growth outcomes in children with HIV (CHIV). Design: Longitudinal study among Kenyan hospitalized ART-naive CHIV in the PUSH trial (NCT02063880)....
9.
Mecha J, Escudero J, Richardson B, Maleche-Obimbo E, Matemo D, Kinuthia J, et al.
Pediatr Infect Dis J . 2023 Nov; 43(3):250-256. PMID: 37991383
Background: The effect of maternal HIV on infant Mycobacterium tuberculosis (Mtb) infection risk is not well-characterized. Methods: Pregnant women with/without HIV and their infants were enrolled in a longitudinal cohort...
10.
Cherkos A, LaCourse S, Kinuthia J, Mecha J, Enquobahrie D, Escudero J, et al.
AIDS . 2023 Nov; 38(4):537-546. PMID: 37967230
Background: Exposure to HIV and antiretroviral therapy (ART) in utero may influence infant growth and development. Most available evidence predates adoption of universal ART (Option B+ ART regimens). In a...