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Jaclyn N Escudero

Explore the profile of Jaclyn N Escudero including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 123
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Recent Articles
1.
Saha A, Escudero J, Layouni T, Mecha J, Maleche-Obimbo E, Matemo D, et al.
Open Forum Infect Dis . 2025 Feb; 12(2):ofaf067. PMID: 39981072
Background: Pregnancy increases (Mtb) reactivation risk and alters immune responses. We assessed Mtb-specific CD4+ T-cell responses in pregnant women with HIV (WLHIV) and without, including those receiving isoniazid preventive therapy...
2.
Day C, Njuguna I, Cranmer L, Whatney W, Pearson R, Arlehamn C, et al.
J Infect Dis . 2024 Dec; PMID: 39693245
Background: Despite immune restoration after initiation of antiretroviral treatment (ART), the risk of tuberculosis (TB) persists in children living with HIV (CLHIV). We determined patterns of immune restoration of mycobacteria-specific...
3.
Cherkos A, LaCourse S, Enquobahrie D, Escudero J, Mecha J, Matemo D, et al.
PLoS One . 2024 Aug; 19(8):e0293708. PMID: 39150949
Background: Isoniazid preventive therapy (IPT) decreases risk of tuberculosis (TB) disease; impact on long-term infant growth is unknown. In a recent randomized trial (RCT), we assessed IPT effects on infant...
4.
LaCourse S, Wetzler E, Aurelio M, Escudero J, Selke S, Greninger A, et al.
J Infect Dis . 2024 Jan; 229(4):1241-1243. PMID: 38285008
No abstract available.
5.
LaCourse S, Wetzler E, Aurelio M, Escudero J, Selke S, Greninger A, et al.
J Infect Dis . 2023 Dec; 229(6):1728-1739. PMID: 38128542
Background: Hybrid immunity (infection plus vaccination) may increase maternally derived SARS-CoV-2 antibody responses and durability versus infection alone. Methods: Prospective cohort of pregnant participants with prior SARS-CoV-2 infection (anti-nucleocapsid IgG,...
6.
Mecha J, Escudero J, Richardson B, Maleche-Obimbo E, Matemo D, Kinuthia J, et al.
Pediatr Infect Dis J . 2023 Nov; 43(3):250-256. PMID: 37991383
Background: The effect of maternal HIV on infant Mycobacterium tuberculosis (Mtb) infection risk is not well-characterized. Methods: Pregnant women with/without HIV and their infants were enrolled in a longitudinal cohort...
7.
Cherkos A, LaCourse S, Kinuthia J, Mecha J, Enquobahrie D, Escudero J, et al.
AIDS . 2023 Nov; 38(4):537-546. PMID: 37967230
Background: Exposure to HIV and antiretroviral therapy (ART) in utero may influence infant growth and development. Most available evidence predates adoption of universal ART (Option B+ ART regimens). In a...
8.
Li L, Lyon C, LaCourse S, Zheng W, Stern J, Escudero J, et al.
Clin Chem . 2023 Nov; 69(12):1409-1419. PMID: 37956323
Background: Novel approaches that allow early diagnosis and treatment monitoring of both human immunodeficiency virus-1 (HIV-1) and tuberculosis disease (TB) are essential to improve patient outcomes. Methods: We developed and...
9.
Cherkos A, LaCourse S, Enquobahrie D, Escudero J, Mecha J, Matemo D, et al.
medRxiv . 2023 Oct; PMID: 37905041
Background: Isoniazid preventive therapy (IPT) decreases risk of tuberculosis (TB) disease; impact on long-term infant growth is unknown. In a recent randomized trial (RCT), we assessed IPT effects on infant...
10.
Escudero J, Mecha J, Richardson B, Maleche-Obimbo E, Matemo D, Kinuthia J, et al.
J Infect Dis . 2023 Sep; 228(12):1709-1719. PMID: 37768184
Background: Pregnancy and human immunodeficiency virus (HIV) may influence tuberculosis infection detection using interferon (IFN)-γ release assay (QFT-Plus; Qiagen) and tuberculin skin test (TST). Methods: Participants in Western Kenya underwent...