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Sylvia Hartmann

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Articles 152
Citations 3324
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Recent Articles
11.
Suske T, Sorger H, Manhart G, Ruge F, Prutsch N, Zimmerman M, et al.
J Clin Invest . 2024 Apr; 134(8). PMID: 38618957
T cell acute lymphoblastic leukemia (T-ALL) is an aggressive immature T cell cancer. Mutations in IL7R have been analyzed genetically, but downstream effector functions such as STAT5A and STAT5B hyperactivation...
12.
Loth A, Fassl A, Chun F, Kollermann J, Hartmann S, Gretser S, et al.
Pathologie (Heidelb) . 2024 Mar; 45(3):211-217. PMID: 38446176
Background: Fluorescence-based confocal microscopy (FCM) can be used to create virtual H&E sections in real time. So far, FCM has been used in dermato-, uro-, and gynecopathology. FCM allows the...
13.
Reinecke R, Jahnke K, Foltyn-Dumitru M, Lachner K, Armbrust M, Weber K, et al.
J Neurochem . 2024 Feb; 168(6):1157-1167. PMID: 38332527
For CNS lymphomas (CNSL), there is a high need for minimally invasive and easily obtainable diagnostic markers. Intrathecal IgM synthesis can easily be determined in routine CSF diagnostics. The aim...
14.
Lorenzi L, Haferlach T, Mori L, Simbeni M, Walter W, Balzarini P, et al.
Haematologica . 2023 Nov; 109(6):1815-1824. PMID: 37994105
Standardized treatment options are lacking for patients with unresectable or multifocal follicular dendritic cell sarcoma (FDCS) and disease-related mortality is as high as 20%. Applying whole-genome sequencing (WGS) in one...
15.
Schleussner N, Cauchy P, Franke V, Giefing M, Fornes O, Vankadari N, et al.
Nat Commun . 2023 Nov; 14(1):6947. PMID: 37935654
Disease-causing mutations in genes encoding transcription factors (TFs) can affect TF interactions with their cognate DNA-binding motifs. Whether and how TF mutations impact upon the binding to TF composite elements...
16.
Ramsower C, Rosenthal A, Robetorye R, Mwangi R, Maurer M, Villa D, et al.
Br J Haematol . 2023 Oct; 204(1):160-170. PMID: 37881141
Mantle cell lymphoma (MCL) is clinically and biologically heterogeneous. While various prognostic features have been proposed, none currently impact therapy selection, particularly in older patients, for whom treatment is primarily...
17.
Rodriguez-Pinilla S, Dojcinov S, Dotlic S, Gibson S, Hartmann S, Klimkowska M, et al.
Virchows Arch . 2023 Oct; 484(6):1041. PMID: 37828242
No abstract available.
18.
Gibson S, Dojcinov S, Dotlic S, Hartmann S, Hsi E, Klimkowska M, et al.
Virchows Arch . 2023 Oct; 484(5):877. PMID: 37828241
No abstract available.
19.
Hartmann S, Yasmeen S, Jacobs B, Denaxas S, Pirmohamed M, Gamazon E, et al.
Nat Commun . 2023 Oct; 14(1):6156. PMID: 37828025
Raynaud's phenomenon (RP) is a common vasospastic disorder that causes severe pain and ulcers, but despite its high reported heritability, no causal genes have been robustly identified. We conducted a...
20.
Kalmbach S, Grau M, Zapukhlyak M, Leich E, Jurinovic V, Hoster E, et al.
Leukemia . 2023 Aug; 37(10):2058-2065. PMID: 37563306
Knowledge on the pathogenesis of FL is mainly based on data derived from advanced/systemic stages of FL (sFL) and only small cohorts of localized FL (lFL) have been characterized intensively...