Sylvia Christakos
Overview
Explore the profile of Sylvia Christakos including associated specialties, affiliations and a list of published articles.
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79
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3437
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Recent Articles
1.
Verlinden L, Li S, Veldurthy V, Carmeliet G, Christakos S
Front Endocrinol (Lausanne)
. 2024 Feb;
15:1310466.
PMID: 38352710
Introduction: Due to the relatively long life span of rodent models, in order to expediate the identification of novel therapeutics of age related diseases, mouse models of accelerated aging have...
2.
Mady L, Zhong Y, Dhawan P, Christakos S
Cells
. 2023 Jul;
12(10).
PMID: 37408241
1,25-Dihydroxyvitamin D3 (1,25(OH)D), the hormonally active form of vitamin D, activates the nuclear vitamin D receptor (VDR) to mediate the transcription of target genes involved in calcium homeostasis as well...
3.
Jiang H, Chanpaisaeng K, Christakos S, Fleet J
Endocrinology
. 2023 Mar;
164(5).
PMID: 36960562
1,25-Dihydroxyvitamin D3 (1,25(OH)2D3)-mediated intestinal calcium (Ca) absorption supplies Ca for proper bone mineralization during growth. We tested whether vitamin D receptor (VDR)-mediated 1,25(OH)2D3 signaling is critical for adult Ca absorption...
4.
Meyer M, Bernal-Mizrachi C, Bikle D, Biyani M, Campbell M, Chaudhari S, et al.
J Steroid Biochem Mol Biol
. 2023 Jan;
228:106247.
PMID: 36639037
The 24th Workshop on Vitamin D was held September 7-9, 2022 in Austin, Texas and covered a wide diversity of research in the vitamin D field from across the globe....
5.
Aita R, Aldea D, Hassan S, Hur J, Pellon-Cardenas O, Cohen E, et al.
J Biol Chem
. 2022 Jul;
298(8):102213.
PMID: 35779631
1,25-dihydroxyvitamin D (VD) regulates intestinal calcium absorption in the small intestine (SI) and also reduces risk of colonic inflammation and cancer. However, the intestine compartment-specific target genes of VD signaling...
6.
Fleet J, Aldea D, Chen L, Christakos S, Verzi M
J Biol Chem
. 2022 Jan;
298(3):101616.
PMID: 35065959
Vitamin D receptor (VDR) levels are highest in the intestine where it mediates 1,25 dihydroxyvitamin D-induced gene expression. However, the mechanisms controlling high intestinal VDR gene expression are unknown. Here,...
7.
Christakos S
JBMR Plus
. 2021 Dec;
5(12):e10554.
PMID: 34950825
Calcium is required for the functioning of numerous biological processes and is essential for skeletal health. The major source of new calcium is from the diet. The central role of...
8.
Criss 2nd Z, Bhasin N, Di Rienzi S, Rajan A, Deans-Fielder K, Swaminathan G, et al.
Physiol Genomics
. 2021 Oct;
53(11):486-508.
PMID: 34612061
Human intestinal epithelial organoids (enteroids and colonoids) are tissue cultures used for understanding the physiology of the human intestinal epithelium. Here, we explored the effect on the transcriptome of common...
9.
Goswami S, Flores J, Balasubramanian I, Bandyopadhyay S, Joseph I, Bianchi-Smak J, et al.
J Cell Physiol
. 2021 Jun;
236(12):8148-8159.
PMID: 34192357
A number of studies have examined the effects of 1,25-dihydroxyvitamin D (1,25(OH) D ) on intestinal inflammation driven by immune cells, while little information is currently available about its impact...
10.
Bouillon R, Haussler M, Bikle D, Christakos S, Welsh J
JBMR Plus
. 2021 Feb;
5(1):e10445.
PMID: 33553991
No abstract available.