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Angela Porta

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Articles 8
Citations 490
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Recent Articles
1.
Dhawan P, Veldurthy V, Yehia G, Hsaio C, Porta A, Kim K, et al.
Endocrinology . 2017 Sep; 158(11):3792-3804. PMID: 28938396
Although the intestine plays the major role in 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] action on calcium homeostasis, the mechanisms involved remain incompletely understood. The established model of 1,25(OH)2D3-regulated intestinal calcium absorption postulates...
2.
Christakos S, Seth T, Hirsch J, Porta A, Moulas A, Dhawan P
Annu Rev Nutr . 2013 May; 33:71-85. PMID: 23642206
Early studies identifying vitamin D as an antirachitic factor led to studies in vitamin D-deficient models that resulted in a basic understanding of the mechanism of action of vitamin D....
3.
Christakos S, Dhawan P, Porta A, Mady L, Seth T
Mol Cell Endocrinol . 2011 Jun; 347(1-2):25-9. PMID: 21664413
The principal function of vitamin D in calcium homeostasis is to increase calcium absorption from the intestine. Calcium is absorbed by both an active transcellular pathway, which is energy dependent,...
4.
Benn B, Ajibade D, Porta A, Dhawan P, Hediger M, Peng J, et al.
Endocrinology . 2008 Mar; 149(6):3196-205. PMID: 18325990
To study the role of the epithelial calcium channel transient receptor potential vanilloid type 6 (TRPV6) and the calcium-binding protein calbindin-D9k in intestinal calcium absorption, TRPV6 knockout (KO), calbindin-D9k KO,...
5.
Christakos S, Dhawan P, Benn B, Porta A, Hediger M, Oh G, et al.
Ann N Y Acad Sci . 2007 Dec; 1116:340-8. PMID: 18083936
Vitamin D maintains calcium homeostasis and is required for bone development and maintenance. Recent evidence has indicated an interrelationship between vitamin D and health beyond bone, including effects on cell...
6.
Liu Y, Porta A, Peng X, Gengaro K, Cunningham E, Li H, et al.
J Bone Miner Res . 2004 Mar; 19(3):479-90. PMID: 15040837
Unlabelled: This study show for the first time that calbindin-D28k can prevent glucocorticoid-induced bone cell death. The anti-apoptotic effect of calbindin-D28k involves inhibition of glucocorticoid induced caspase 3 activation as...
7.
Song Y, Peng X, Porta A, Takanaga H, Peng J, Hediger M, et al.
Endocrinology . 2003 Aug; 144(9):3885-94. PMID: 12933662
We examined the expression of calcium transporter 1 (CaT1) and epithelial calcium channel (ECaC) mRNA in the duodenum and kidney of mice. Intestinal CaT1 mRNA level increased 30-fold at weaning,...
8.
Christakos S, Dhawan P, Liu Y, Peng X, Porta A
J Cell Biochem . 2003 Feb; 88(4):695-705. PMID: 12577303
The biologically active metabolite of vitamin D, 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) is a secosteroid whose genomic mechanism of action is similar to that of other steroid hormones and is mediated by...