Swetha Parvathaneni
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Explore the profile of Swetha Parvathaneni including associated specialties, affiliations and a list of published articles.
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17
Citations
339
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Recent Articles
1.
Lotspeich-Cole L, Parvathaneni S, Sakai J, Liu L, Takeda K, Lee R, et al.
NPJ Vaccines
. 2024 May;
9(1):92.
PMID: 38796539
Neonates and young infants are known to have limited responses to pediatric vaccines due to reduced germinal center formation. Extended vaccine antigen dosing was previously shown to expand germinal center...
2.
Parvathaneni S, Yang J, Lotspeich-Cole L, Sakai J, Lee R, Akkoyunlu M
NPJ Vaccines
. 2023 Nov;
8(1):173.
PMID: 37938563
The inability of neonates to develop CD4FoxP3CXCR5PD-1 T follicular helper (T) cells contributes to their weak vaccine responses. In previous studies, we measured diminished IgG responses when IL-6 was co-injected...
3.
Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species
Martin-Vega A, Ruiz-Peinado L, Garcia-Gomez R, Herrero A, de la Fuente-Vivas D, Parvathaneni S, et al.
Sci Adv
. 2023 Feb;
9(7):eadd7969.
PMID: 36791195
RAS-ERK (extracellular signal-regulated kinase) pathway signals are modulated by scaffold proteins that assemble the components of different kinase tiers into a sequential phosphorylation cascade. In the prevailing model scaffold proteins...
4.
Parvathaneni S, Li Z, Sacks D
J Biol Chem
. 2021 Mar;
296:100577.
PMID: 33766558
The mitogen-activated protein kinase (MAPK) cascade is a fundamental signaling pathway that regulates cell fate decisions in response to external stimuli. Several scaffold proteins bind directly to kinase components of...
5.
Lu X, Redon C, Tang W, Parvathaneni S, Bokhari B, Debnath S, et al.
Mol Cell Biol
. 2021 Jan;
41(4).
PMID: 33468559
Susceptibility to breast cancer is significantly increased in individuals with germ line mutations in (also known as or ), a gene encoding a DNA helicase essential for genome maintenance. We...
6.
Hedman A, Li Z, Gorisse L, Parvathaneni S, Morgan C, Sacks D
J Biol Chem
. 2020 Nov;
296:100075.
PMID: 33191271
AMP-activated protein kinase (AMPK) is a fundamental component of a protein kinase cascade that is an energy sensor. AMPK maintains energy homeostasis in the cell by promoting catabolic and inhibiting...
7.
Sharma P, Alsharif S, Bursch K, Parvathaneni S, Anastasakis D, Chahine J, et al.
Sci Rep
. 2019 Oct;
9(1):14650.
PMID: 31601969
Keratin 19 (K19) belongs to the keratin family of proteins, which maintains structural integrity of epithelia. In cancer, K19 is highly expressed in several types where it serves as a...
8.
Parvathaneni S, Sharma S
J Biol Chem
. 2019 Aug;
294(42):15330-15345.
PMID: 31444271
The response of cancer cells to therapeutic drugs that cause DNA damage depends on genes playing a role in DNA repair. RecQ-like helicase 1 (RECQ1), a DNA repair helicase, is...
9.
Parvathaneni S, Lu X, Chaudhary R, Lal A, Madhusudan S, Sharma S
Oncotarget
. 2017 Nov;
8(44):75924-75942.
PMID: 29100281
Sensitivity of cancer cells to DNA damaging chemotherapeutics is determined by DNA repair processes. Consequently, cancer cells may upregulate the expression of certain DNA repair genes as a mechanism to...
10.
Li X, Subramanian M, Jones M, Chaudhary R, Singh D, Zong X, et al.
Cell Rep
. 2017 Sep;
20(10):2408-2423.
PMID: 28877474
Basal p53 levels are tightly suppressed under normal conditions. Disrupting this regulation results in elevated p53 levels to induce cell cycle arrest, apoptosis, and tumor suppression. Here, we report the...