Swati S Jain
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Explore the profile of Swati S Jain including associated specialties, affiliations and a list of published articles.
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20
Citations
500
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Recent Articles
1.
Holloway G, Nickerson J, Lally J, Petrick H, Dennis K, Jain S, et al.
Am J Physiol Cell Physiol
. 2022 Feb;
322(3):C546-C553.
PMID: 35138177
We aimed to determine the combined effects of overexpressing plasma membrane fatty acid binding protein (FABPpm) and fatty acid translocase (CD36) on skeletal muscle fatty acid transport to establish if...
2.
Whitfield J, Paglialunga S, Smith B, Miotto P, Simnett G, Robson H, et al.
J Biol Chem
. 2017 Aug;
292(40):16653-16664.
PMID: 28808062
TBC1 domain family member 1 (TBC1D1), a Rab GTPase-activating protein and paralogue of Akt substrate of 160 kDa (AS160), has been implicated in both insulin- and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase-mediated...
3.
Momken I, Chabowski A, Dirkx E, Nabben M, Jain S, McFarlan J, et al.
Biochem J
. 2016 Nov;
474(1):149-162.
PMID: 27827305
Leptin stimulates fatty acid oxidation in muscle and heart; but, the mechanism by which these tissues provide additional intracellular fatty acids for their oxidation remains unknown. We examined, in isolated...
4.
Jain S, Luiken J, Snook L, Han X, Holloway G, Glatz J, et al.
FEBS Lett
. 2015 Aug;
589(19 Pt B):2769-75.
PMID: 26296318
Muscle contains various fatty acid transporters (CD36, FABPpm, FATP1, FATP4). Physiological stimuli (insulin, contraction) induce the translocation of all four transporters to the sarcolemma to enhance fatty acid uptake similarly...
5.
Bonen A, Jain S, Snook L, Han X, Yoshida Y, Buddo K, et al.
Diabetologia
. 2015 Jul;
58(10):2381-91.
PMID: 26197708
Aims/hypothesis: The mechanisms for diet-induced intramyocellular lipid accumulation and its association with insulin resistance remain contentious. In a detailed time-course study in rats, we examined whether a high-fat diet increased...
6.
Monaco C, Whitfield J, Jain S, Spriet L, Bonen A, Holloway G
PLoS One
. 2015 May;
10(5):e0126122.
PMID: 25965390
Exercise has been shown to induce the translocation of fatty acid translocase (FAT/CD36), a fatty acid transport protein, to both plasma and mitochondrial membranes. While previous studies have examined signals...
7.
Davis M, Bonen A, Snook L, Jain S, Bartels K, Geor R, et al.
PLoS One
. 2014 Jul;
9(7):e103087.
PMID: 25075856
Endurance exercise relies on transsarcolemmal flux of substrates in order to avoid depletion of intramuscular reserves. Previous studies of endurance trained sled dogs have shown a remarkable capacity of these...
8.
Matravadia S, Herbst E, Jain S, Mutch D, Holloway G
Am J Physiol Endocrinol Metab
. 2014 May;
307(1):E102-14.
PMID: 24844257
The therapeutic use of polyunsaturated fatty acids (PUFA) in preserving insulin sensitivity has gained interest in recent decades; however, the roles of linoleic acid (LA) and α-linolenic acid (ALA) remain...
9.
Jain S, Paglialunga S, Vigna C, Ludzki A, Herbst E, Lally J, et al.
Diabetes
. 2014 Feb;
63(6):1907-13.
PMID: 24520120
Calcium/calmodulin-dependent protein kinase (CaMK) activation induces mitochondrial biogenesis in response to increasing cytosolic calcium concentrations. Calcium leak from the ryanodine receptor (RyR) is regulated by reactive oxygen species (ROS), which...
10.
Holloway G, Han X, Jain S, Bonen A, Chabowski A
Diabetologia
. 2014 Jan;
57(4):832-40.
PMID: 24458200
Aims/hypothesis: Although insulin resistance has been associated with accumulations of specific intramuscular fatty acids and altered subcellular localisation of lipid droplets, these concepts remain controversial. Therefore, we aimed to identify...